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首页> 外文会议>International Conference on Biomedical and Biological Engineering >Concentrations of Trace Elements in Different types of Gallstones and Their Effects on Gallstone Formation
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Concentrations of Trace Elements in Different types of Gallstones and Their Effects on Gallstone Formation

机译：不同类型胆结石中微量元素的浓度及其对胆结石形成的影响

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Purpose: To study the concentrations of trace metals and nonmetals elements in different types of gallstones (cholesterol-, pigment-, mixed- and calcium carbonate type) and to explore the formation mechanisms of gallstones. Method: Inductively coupled plasma emission spectrometer (ICP-AES) was used to determine the concentrations of calcium, manganese, magnesium, iron, copper, zinc, sulfur, and phosphorus. Results: Calcium, copper, sulfur and phosphorus play important roles in the formation of pigment stones. High concentrations of Cu~(2+) and Ca~(2+) ions can coordinate with bilirubin to form calcium bilirubinate and copper bilirubinate, respectively; phosphorus and sulfur suggest the presence of proteins in gallstones, and some proteins (such as mucin) can promote the formation of gallstones. Conclusions: The contents of metal and nonmetal elements in gallstones can accurately be detected using ICP-AES. The formation of different types of gallstones is closely related to the difference of these elements. This study is of great significance to reveal the cause of gallstones formation.
机译：目的：研究不同类型的胆结石（胆固醇，颜料，混合和碳酸钙型）中痕量金属和非金属元素的浓度，并探讨胆结石的形成机制。方法：电感耦合等离子体发射光谱仪（ICP-AES）用于确定钙，锰，镁，铁，铜，锌，硫和磷的浓度。结果：钙，铜，硫和磷在颜料结石的形成中起重要作用。高浓度的Cu〜（2+）和Ca〜（2+）离子可以与胆红素坐标，以分别形成胆胆钙和铜胆胆钠;磷和硫建议在胆结石中存在蛋白质，并且一些蛋白质（例如粘蛋白）可以促进胆结石的形成。结论：使用ICP-AES可以准确地检测胆结石中金属和非金属元素的含量。不同类型的胆结石的形成与这些元素的差异密切相关。本研究具有重要意义，揭示了胆结石形成的原因。

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