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Analysis of the Results of Replacement of Large Bone Defects in the Patients Who Underwent Segmental Bone Resection for Tumor

机译:对肿瘤节段骨切除术后患者替代大骨缺陷的结果分析

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The problem of large bone defects replacement, formed after segmental bone resections, remains an actual issue of modern orthopedics. It is known that the autograft is the most acceptable material for the replacement of bone tissue; however, due to its small volume and physical properties, it has limited usage. Our goal is to analyze the results of the experiments and studies on replacement of large bone defects after resection of the bone tumor. The problem is justified by the complicated osteoconduction and osteointegration; because it is proved that the reconstruction of the microcirculatory bloodstream is difficult in the presence of damage more than 4 cm~2. It was revealed that using of allograft in combination with additional components is comparable in effectiveness, including long-term period, with autograft usage. It is promising to combine plastic allogenous material, capable of reconstructing defects of various configuration intraoperatively, with the necessary chemotherapy with controlled desorption to maintain effective concentration of drug.
机译:在节段骨切除后形成的大骨缺陷替代的问题仍然是现代骨科的实际问题。众所周知,自体移植是更换骨组织的最可接受的材料;但是,由于其体积较小和物理性质,使用量有限。我们的目标是分析实验的结果和研究在切除骨肿瘤后更换大骨缺损。问题是由复杂的疏松和骨骼整治的合理;因为证明,在存在超过4cm〜2的损伤存在下,微循环性血液的重建难以。据透露,同种异体移植物与附加组分的组合是可比的,包括长期期间,具有自体移植的使用。它很有希望结合塑料交联物质,能够术中重建各种配置的缺陷,具有控制解吸的必要化疗,以维持有效的药物浓度。

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