首页> 外文会议>Conference on Optical Coherence tomography and coherence domain optical methods in biomedicine XXI >Speckle variance full-field optical coherence microscopy for high-resolution microvasculature mapping
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Speckle variance full-field optical coherence microscopy for high-resolution microvasculature mapping

机译:散斑差异全场光相干显微镜用于高分辨率微孔弹性测绘

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This work reports on the feasibility of dynamic imaging using conventional reflectivity-based tomographic images obtained with full-field optical coherence microscopy (FF-OCM). Implementation of speckle variance for flow mapping with an imaging rate of 180 Hz is demonstrated by mapping 20% intralipid flowing into 100-μm-diameter microcapillary tubes at speeds up to ~ 50 mm/s. This constitutes a significant advance in high-resolution, real-time microvasculature mapping, using FF-OCM. The acquisition scheme in FF-OCM is particularly appropriate for en face visualization of the microvasculature, as FF-OCM directly acquires en face tomographic images unlike conventional OCT which usually requires reslicing of a three-dimensional data set to get en face images.
机译:该工作报告了使用用全场光学相干显微镜(FF-OCM)获得的传统基于反射率的断层图像的动态成像的可行性。通过将20%的胰蛋白体在高达约〜50mm / s的速度下映射到100μm-直径的微毛管,通过将20%的胰蛋白酶映射到〜50mm / s的速度来证明具有180Hz的成像速率的流动映射的散斑差异的实现。这构成了使用FF-OCM的高分辨率,实时微血管系统映射的显着提前。 FF-OCM中的采集方案特别适用于对微孔径的面部可视化,因为FF-OCM直接获取与传统的OCT不同的en面断层图像,这通常需要重新选择三维数据集以获得en面部图像。

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