Birefringence and vascular imaging of in vivo human skin by Jones-matrix optical coherence tomography

机译：Jones-Matrix光学相干断层扫描的体内人体皮肤的双折射和血管成像

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A customized 1310-nm Jones-matrix optical coherence tomography (JM-OCT) for dermatological investigation was constructed and used for in vivo normal human skin tissue imaging. This system can simultaneously measure the three-dimensional depth-resolved local birefringence, complex-correlation based OCT angiography (OCT-A), degree-of-polarization-uniformity (DOPU) and scattering OCT intensity. By obtaining these optical properties of tissue, the morphology, vasculature, and collagen content of skin can be deduced and visualized. Structures in the deep layers of the epithelium were observed with depth-resolved local birefringence and polarization uniformity images. These results suggest high diagnostic and investigative potential of JM-OCT for dermatology.

机译：构建了用于皮肤病学研究的定制的1310-nm jones-matrix光学相干断层扫描（JM-OCT），并用于体内正常人体皮肤组织成像。该系统可以同时测量三维深度分辨的局部双折射，基于基于血管造影（OCT-A）的复杂相关性，偏振程度均匀（DOPU）和散射OCT强度。通过获得组织的光学性质，可以推断和可视化皮肤的形态，脉管系统和胶原醛含量。用深度分辨的局部双折射和偏振均匀性图像观察上皮的深层中的结构。这些结果表明JM-OCT的皮肤科的高诊断和调查潜力。

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《Conference on Optical Coherence tomography and coherence domain optical methods in biomedicine XXI》|2017年|v. p.|共5页
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En Li; Shuichi Makita; Young-Joo Hong; Deepa Kasaragod; Yoshiaki Yasuno;
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中图分类生物医学工程;
关键词
optical coherence tomography; skin; local birefringence; collagen; polarization; vasculature;

机译：光学相干断层扫描;皮肤;局部双折射;胶原;极化;血管系统;

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专利

1. Imaging of skin birefringence for human scar assessment using polarization-sensitive optical coherence tomography aided by vascular masking [J] . Peijun Gong, Lixin Chin, Shaghayegh Eshaghian, Journal of biomedical optics . 2014,第12期

机译：使用偏振敏感的光学相干断层扫描和血管遮盖术对皮肤双折射成像，以评估人的疤痕
2. Phase-resolved functional optical coherence tomography: simultaneous imaging of in situ tissue structure, blood flow velocity, standard deviation, birefringence, and Stokes vectors in human skin [J] . Hongwu Ren, Zhihua Ding, Yonghua Zhao, Optics Letters . 2002,第19期

机译：相分辨功能光学相干断层扫描：同时成像人体皮肤中的原位组织结构，血流速度，标准偏差，双折射和斯托克斯向量
3. Birefringence imaging of human skin by polarization-sensitive spectral interferometric optical coherence tomography [J] . Y. Yasuno, S. Makita, Y. Sutoh, Optics Letters . 2002,第20期

机译：偏振敏感光谱干涉光学相干层析成像技术对人皮肤的双折射成像
4. Birefringence and vascular imaging of in vivo human skin by Jones-matrix optical coherence tomography [C] . En Li, Shuichi Makita, Young-Joo Hong, Optical Coherence tomography and coherence domain optical methods in biomedicine XXI . 2017

机译：琼斯矩阵光学相干层析成像技术对人体内皮肤的双折射和血管成像
5. Fourier-domain Optical Coherence Tomography for in vivo Human Retinal Imaging [D] . Kim, DaeYu 2011

机译：体内人类视网膜成像的傅里叶域光学相干断层扫描。
6. Combined multi-modal photoacoustic tomography optical coherence tomography (OCT) and OCT angiography system with an articulated probe for in vivo human skin structure and vasculature imaging [O] . Mengyang Liu, Zhe Chen, Behrooz Zabihian, 2016

机译：结合了多模态光声层析成像光学相干层析成像（OCT）和OCT血管造影系统以及用于活体人体皮肤结构和脉管系统成像的铰接式探头
7. Phase-resolved functional optical coherence tomography: simultaneous imaging of in situ tissue structure, blood flow velocity, standard deviation, birefringence, and Stokes vectors in human skin [O] . Hongwu Ren, Zhihua Ding, Yonghua Zhao, 2002

机译：相位分辨的功能光学相干断层扫描：人体皮肤中的原位组织结构，血流速度，标准偏差，双折射和斯托克斯载体的同时成像

Birefringence and vascular imaging of in vivo human skin by Jones-matrix optical coherence tomography

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