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Coagulation monitoring based on blood elastic measurement using optical coherence tomography

机译:基于光学弹性测量光学相干断层扫描的凝血监测

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Blood coagulation monitoring is important to diagnose hematological diseases and cardiovascular diseases and to predict the risk of bleeding and excessive clotting. In this study, we developed a system to dynamically monitor blood coagulation and quantitatively determine the coagulation function by blood elastic measurement. When blood forms a clot from a liquid, ultrasonic force induces a shear wave, which is detected by optical coherence tomography (OCT). The coagulation of porcine whole blood recalcified by calcium chloride is assessed using the metrics of reaction time, clot formation kinetics and maximum shear modulus. The OCE system can noninvasively monitor the blood coagulation and quantitatively determine the coagulation function.
机译:血液凝固监测对于诊断血液疾病和心血管疾病是重要的,并预测出血和过度凝血的风险。在这项研究中,我们开发了一种动态监测血液凝固的系统,并通过血弹测量定量地确定凝血功能。当血液从液体形成凝块时,超声力引起剪切波,通过光学相干断层扫描(OCT)检测。使用反应时间,凝块形成动力学和最大剪切模量来评估通过氯化钙重新计算的猪全血的凝血。 OCE系统可以非侵略地监测血液凝固并定量地确定凝血功能。

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