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Contrast improvement for swept source optical coherence tomography image of sub-surface tissue

机译:扫掠源光学相干断层摄影图像的对比改善亚表面组织

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Swept source optical coherence tomography (SSOCT) is an attractive biological imaging technology due to its advantages of simple setup and high imaging speed. As the light intensity attenuated rapidly in high scattering biological tissues, the contrast of OCT image will drop with depth. In this paper a new method was introduced to compensate the attenuation of imaging contrast in SSOCT. The interference signal was divided into two channels of analog to digital converter (ADC) with a splitting ratio of 1:5. The higher level signal in one channel was used to reconstruct deeper structure of tissue and the lower level signal in the other channel was used to reconstruct surface structure of tissue. Low-frequency signals in one channel were filtered by a high pass filter and then combined with the signal in the other channel to obtain a high contrast image in both surface and deep area of tissue. Human finger and porcine airway imaging obtained with the system show that the contrast of SSOCT images can be improved in deeper region of tissue.
机译:扫描源光学相干断层扫描(SSOCT)是一种有吸引力的生物成像技术,因为它具有简单的设置和高成像速度。随着在高散射生物组织中快速减弱的光强度,OCT图像的对比度将落下深度。在本文中,引入了一种新方法以补偿SSOCT中成像对比度的衰减。干扰信号被分成两种模数转换器(ADC)的通道,分裂比为1:5。一个通道中的较高级别信号用于重建组织的更深层面结构,并且其他通道中的较低级别信号用于重建组织的表面结构。在一个通道中的低频率信号通过的高通滤波器过滤,然后用在其它信道的信号组合以获得在两个表面和组织的深部区域的高对比度图像。用系统获得的人体手指和猪气道成像表明SSOCT图像的对比度可以在更深的组织区域中得到改善。

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