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Effects of Oral Glutathione Precursors' Supplementation on Human Glutathione Level

机译:口服谷胱甘肽前体对人类谷胱甘肽水平补充的影响

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Glutathione (GSH) is a tripeptide of cysteine, glutamate, and glycine. These amino acids made the synthesis of GSH possible and act as a major cellular antioxidant in the body. The production of GSH in the body depends on several factors; such as dietary intake and cysteine availability. With the turnover rate of endogenous GSH can be as high as 65% per day, more consumers has turned to GSH supplement to maintain or boost up their GSH level. GSH supplement available in the market usually contains GSH precursor/s that are said to be able to increase GSH level in the body. In this study, the oral GSH supplement used contains all three precursors of GSH; cystine replacing cysteine, glutamate, and glycine. Subjects were asked to consume the supplement according to the instructed dosage in order to measure the effects of oral GSH precursors' supplement on human GSH level after the three-month study period ends. The results from this study suggest that the oral GSH precursors' supplement increases GSH level across the test groups after the three-month study period.
机译:谷胱甘肽(GSH)是半胱氨酸,谷氨酸和甘氨酸的三肽。这些氨基酸使GSH的合成成为可能,并充当体内的主要细胞抗氧化剂。身体中GSH的生产取决于几个因素;如膳食摄入和半胱氨酸可用性。随着内源性GSH的周转率可以高达每天65%,更多的消费者转向GSH补充以维持或提高他们的GSH水平。市场上可用的GSH补充通常包含GSH前体/ S,据说能够增加身体的GSH水平。在这项研究中,使用的口腔GSH补充剂含有全部三个GSH;胱氨酸取代半胱氨酸,谷氨酸和甘氨酸。要求受试者根据指示的剂量消耗补充剂,以便在三个月的研究期结束后测量口服GSH前体性对人类GSH水平的影响。本研究结果表明,在三个月的研究期后,口服GSH前体的补充剂在测试组中增加了GSH水平。

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