• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>International Symposium on Current Progress in Mathematics and Sciences >Modification of Curcumin from Turmeric Rhizome (Curcuma longa) Extract Through O-ethylation with K_2CO_3/TBAB Catalyst to Enhance Its Antibacterial Activity
【24h】

Modification of Curcumin from Turmeric Rhizome (Curcuma longa) Extract Through O-ethylation with K_2CO_3/TBAB Catalyst to Enhance Its Antibacterial Activity

机译：通过用K_2CO_3 / TBAB催化剂通过O-乙基催化剂来改变姜黄素从姜黄（Curcuma longa）提取催化剂以增强其抗菌活性

获取原文
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Curcumin is a polyphenol compound contained in turmeric rhizome plants, and determines its pharmacological activity. Modification of curcumin structure has been explored to increase the lipophilicity of curcumin. The increase of lipophilicity is expected to enhance its bioactivity. This study aims to modify hydroxyl groups of curcumin by O-ethylation with diethyl carbonate that is environmentally friendly. Curcumin was modified into diethyl curcumin with a K_2CO_3 base catalyst under reflux conditions. TBAB (tetrabutylammonium bromide), as a Phase Transfer Catalyst (PTC), is added to this reaction system and has been shown to improve the synthesis results. The product has obtained percent yield of 89 % and characterized as diethyl curcumin. Curcumin and diethyl curcumin have shown an antibacterial activity against the growth of Gram-negative Escherichia coli bacteria, but did not inhibit the growth of Gram-positive Staphylococcus aureus bacteria.
机译：姜黄素是姜黄茎植物中含有的多酚化合物，并确定其药理活性。 已经探讨了姜黄素结构的改性以增加姜黄素的亲脂性。 预计亲脂性的增加会增强其生物活性。 该研究旨在通过邻碳酸酯的碳酸酯来改变姜黄素的羟基羟基酯。 在回流条件下用K_2CO_3基础催化剂将姜黄素改性为二乙基姜黄素。 作为相转移催化剂（PTC）的TBAB（四丁基溴化铵）加入到该反应体系中，并已被证明以改善合成结果。 该产物获得了89％的百分比百分比，其特征为二乙基姜黄素。 姜黄素和二乙基姜黄素显示出抗菌活性，免受革兰氏阴性大肠杆菌细菌的生长，但没有抑制革兰氏阳性金黄色葡萄球菌的生长。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号