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首页> 外文会议>International Conference on "Times of Polymers and Composites" >Evaluating the reliability of a cantilever biosensor for disease or cell detection
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Evaluating the reliability of a cantilever biosensor for disease or cell detection

机译：评估悬臂生物传感器对疾病或细胞检测的可靠性

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Micro/nano cantilever represents the recent most diffuse mechanical biosensor since there are two main modes in which can be operated: static bending and dynamic resonance frequency shift. In the former case, it responds mechanically to changes in the surface stresses on its surfaces due to the adsorption of the analyte that cover the surface area of the sensor with a uniform film. In the latter case, it responds mechanically by changing the resonance frequency due to the deposited cell mass on an added layer. Nonetheless, the limited range of applicability of the equations proposed for the biodetection may hinder their easy use as biomolecular sensors on real-time biological assays. The main factors that limit their reliability are :the presence of real interfacial slip, the dependence of the resonance frequency on the cell position and the strong reduction of the mass resolution due to the damping effect of the liquid medium.
机译：微/纳米悬臂代表最近的大多数漫射机械生物传感器，因为有两个主要模式可以操作：静态弯曲和动态谐振频率。在前一种情况下，由于覆盖传感器的表面积的分析物的吸附，它可以机械地响应其表面上的表面应力的变化。在后一种情况下，它通过改变由于沉积的电池质量在添加的层上而通过改变共振频率来机械地响应。尽管如此，为生物竞选提出的等式的有限范围的适用性可能会阻碍其在实时生物测定中作为生物分子传感器的容易用途。限制其可靠性的主要因素是：存在真实界面滑动，谐振频率对电池位置的依赖性以及由于液体介质的阻尼效应而强度降低的质量分辨率。

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