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首页> 外文会议>International Seminar on Chemistry >Antioxidant Activity against Hydrogen Peroxide-Induced Cytotoxicity of Euphorbia Hirta L.
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Antioxidant Activity against Hydrogen Peroxide-Induced Cytotoxicity of Euphorbia Hirta L.

机译：抗氧化活性对过氧化氢诱导的大戟属Hirta L1的细胞毒性。

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Euphorbia hirta L. has been proved a medicinally important plant. This study aimed to investigate the antioxidant capacities of fractioned extracts and some isolated compounds from Euphorbia hirta L. on pancreatic β-cells MIN6 exposed to hydrogen peroxide-oxidative stress conditions. Four pure compounds were isolated from ethyl acetate and methanol extracts and identified as quercitrin (1), luteolin (2), quercetin (3) and caffeic acid (4). The results showed that the ethyl acetate extract as well as quercetin possess strong protective effects with the cell viability of 81% and 82% at the dose of 0.1 mg/mL. This proves that E hirta L. is a potentially natural antioxidative plant and worth testing for further pharmacological potential in the treatment of oxidative stress which may be related to neurodegenerative diseases.
机译：大戟属Hirta L.已被证明是一种药用的植物。本研究旨在研究分馏提取物和来自大戟属Hirta L1的抗氧化能力和一些分离的化合物。在暴露于过氧化氢 - 氧化胁迫条件下的胰腺β细胞Min6上。从乙酸乙酯和甲醇提取物中分离出四种纯化合物，并鉴定为槲皮素（1），叶黄素（2），槲皮素（3）和咖啡酸（4）。结果表明，乙酸乙酯提取物以及槲皮素具有强大的保护作用，其细胞活力为81％和82％，剂量为0.1mg / ml。这证明了E Hirta L.是一种潜在的天然抗氧化植物，可用于治疗氧化应激的进一步药理潜力，这可能与神经变性疾病有关。

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