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首页> 外文会议>Advanced Topics in Optoelectronics, Microelectronics, and Nanotechnologies >Optoelectronic method for the determination of synthetic cannabinoids and their metabolites
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Optoelectronic method for the determination of synthetic cannabinoids and their metabolites

机译：用于测定合成大麻素及其代谢物的光电方法

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摘要

Establishing an optoelectronic method for the determination of synthetic cannabinoids and their metabolites is necessary because synthetic cannabinoids are a group of psychoactive compounds designed to mimic the effects of marijuana. These compounds are usually sprayed on natural plants in order to be smoked. Several synthetic cannabinoids can be found on these smoked plants simultaneously. Their effective dose is lower than that of natural marijuana but with high psychoactive potency [1]. Due to their high potential for abuse and availability, these compounds are considered to be narcotic drugs. Thus, there has been an increased demand for the development of sensitive, reliable, robust and sustainable analytical methods for the identification and quantification of these compounds by clinical, forensic and toxicological laboratories [2]. The method presented in the paper will be based on liquid chromatography with a mass spectrometer detector (LCMS/ MS). The paper aims to obtain, using the developed method, the mass spectra of synthetic cannabinoids and their metabolites. The mass spectrum represents the relative abundance of ions resulting from an ionization process of a family of molecules. This is a unique feature for each compound, which allows identification of a substance from a matrix of unknown substances [3].
机译：建立的光电子方法用于合成大麻素和它们的代谢物的确定，因为合成大麻素是一组设计成模拟大麻的影响精神活性化合物是必要的。这些化合物通常以喷洒在天然植物被熏。一些合成大麻素可以在这些植物熏同时被发现。他们的有效剂量是比天然大麻，但具有高效力精神[1]低。由于其滥用和可用性高的潜力，这些化合物被认为是毒品。因此，存在对用于这些化合物的鉴定和定量灵敏，可靠，坚固的和可持续的分析方法由临床，法医和毒理学实验室[2]的发展的需求增加。在本文所提出的方法将基于用质谱仪检测器（LCMS / MS）的液相色谱。本文旨在获得，使用所提出的方法，合成大麻素以及它们的代谢物的质谱。质谱表示从分子家族的电离过程中产生的离子的相对丰度。这是对每个化合物，这允许物质的识别从未知物质[3]的矩阵的独特功能。

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