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The Protective role of aqueous extract of grape seeds Vitis vinifera in some biochemical parameters and histological changes in methionine for liver, kidney and heart in mice (Mus musculus)

机译:葡萄种子水提取物的保护作用在肝脏,肾脏和小鼠中甲硫氨酸中的一些生化参数和组织学变化中的作用(Mus Musculus)

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The current study was conducted for the period (10/4/2019 to 1/6/2019) on the white mouse of Swiss origin for the purpose of demonstrating the effect of methionine on the appearance of tissue lesions of some members and the possibility of treatment with extract grape seeds , And used 16 animals of white mice for this purpose, was used oral dosage of methionine dosage for 10 days and treatment with grape extract for 30 days .The results of the study of the histopathological effects in the liver, kidney and heart tissues of the groups treated with methionine showed changes in the tissues of the heart, liver and kidneys, which were characterized by the presence of hemorrhage, lymphocyte infiltration, necrosis of cell cytoplasts, and nucleus. The fourth group, which included the best grape seed extract group among the three concentration groups of the three aquatic extracts, showed a very good improvement compared to the first and the second group and the third group where the closest natural form of the tissue was found in the control group, This is due to the different susceptibility of the body of the animal used in the study to the similarity of treatment with the extract of the seeds of aqueous grapes. And that the level of enzymes decreased when treated with methionine and that the levels approached the control group when treatment with the extract of water grapes with increasing concentrations.
机译:目前的研究是为对小白鼠瑞士血统的周期(2019年10月4日至2019年1月6日)用于证实对一些成员的组织损伤的外观蛋氨酸的效果的目的,的可能性进行用提取物葡萄种子处理,并使用16只白鼠的动物为此目的,用甲硫氨酸剂量的口服剂量10天,并用葡萄萃取物处理30天。肝脏肝脏组织病理学作用的研究结果用甲硫氨酸处理的组的心脏组织显示出心脏,肝脏和肾脏的组织的变化,其特征在于出血,淋巴细胞浸润,细胞瘤细胞瘤的坏死和细胞核。包括三个水生提取物的三个浓度组中最好的葡萄种子提取物组的第四组表现出与第一组和第二组和第三组相比的良好改善,其中发现了最近的组织自然形式的组织在对照组中,这是由于在研究中使用的动物体内的易感性与水性葡萄种子提取物的治疗相似性。当用甲硫氨酸处理时,酶的水平降低,并且当用水葡萄提取物随着浓度的增加时,水平接近对照组。

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