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Effect of Yifukang oral liquid on gastric emptying and intestinal peristalsis in mice

机译：Yifukang口服液对小鼠胃排空和肠蠕动的影响

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To observe the effect of Yifukang oral liquid on gastric emptying and intestinal peristalsis in mice. Methods: 60 mice were randomly divided into 5 groups. The suspension of Baohe Pill and the same volume of normal saline group were given once a day for 7 days. After the last administration for 30 minutes, 0.25 ml of 0.04% phenolic red solution was administered by stomach. After 20 minutes, the animals were killed, the stomach was removed, the gastric contents were cleaned, and the lotion 5ml was centrifuged. The absorbance of the supernatant was measured by TU-1901 ultraviolet spectrophotometer at the wavelength of 560nm. The residual rate of gastric phenolic red was calculated. Rate was used to evaluate gastric emptying velocity.60 mice were randomly divided into five groups: group 5, large, medium, small Yifukang oral liquid dosage group, pill suspension and the same volume normal saline. After 20 min after the last dose of carbon powder suspension, the mice were sacrificed, the abdominal cavity was cut open, the intestine of the ileocecum was cut off, the intestinal mesentery was separated, the total length of the small intestine (cm) was measured, and the distance (cm) in the small intestine was measured, and the end-of-carbon propulsion rate was calculated. Compared with the blank group, small dose of Yi Fu Kang group and Baohe Pill group could significantly promote the ability of gastric emptying in mice. Compared with the blank group, small dose group and rehabilitation benefits Baohewan group can significantly promote the gastric emptying ability of mice (P<0.01), high dose group had no obvious benefit rehabilitation ability to promote gastric emptying in mice. Yi Fu Kang oral liquid group could significantly increase the percentage of small intestine carbon powder(P<0.01), Large, medium-dose Yifukang oral liquid and Baofuwan group could significantly increase the percentage of small intestinal carbon in mice (P<0.05). Yi Fukang oral liquid has the effect of promoting gastric emptying and small intestinal peristalsis.
机译：观察Yifukang口服液对小鼠胃排空和肠蠕动的影响。方法：将60只小鼠随机分为5组。宝河丸和相同体积的生理盐水组的悬浮液每天给予每天7天。在最后一次给药后30分钟后，通过胃给予0.25ml 0.25％的酚醛红色溶液。 20分钟后，将动物杀死，除去胃，清洁胃内容物，将乳液5ml离心。通过Tu-1901紫外分光光度计测量上清液的吸光度，在560nm的波长下测量。计算胃酚醛红色的残余速率。速率用于评估胃排空速度.60小鼠随机分为五组：第5组，大，中，小义乌应液剂量组，药丸悬浮液和相同的盐水。在最后一次剂量的碳粉悬浮液后20分钟后，处死小鼠，切断腹腔，切断肠肠的肠道，分离肠肠系膜，小肠（cm）的总长度是测量测量小肠中的距离（cm），并计算碳结束的推进率。与空白组相比，小剂量的易富康集团和宝河丸组可以显着促进胃排空的小鼠的能力。与空白组相比，小剂量组和康复益处宝Hewan集团可以显着促进小鼠的胃排空能力（P <0.01），高剂量组没有明显的恢复能力，促进小鼠胃排空。易益康口服液液体可显着增加小肠碳粉的百分比（P <0.01），大，中剂量义乌·少年液体和宝富华组可显着增加小鼠小肠碳的百分比（P <0.05）。易福康口服液具有促进胃排空和小肠蠕动的效果。

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