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Effect of Qingnao tablet on blood viscosity of rat model of blood stasis induced by epinephrine

机译:青穗片对肾上腺素诱导的血瘀模型血液粘度的影响

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To establish a rat model of blood stasis with adrenaline (Adr) subcutaneous injection and ice bath stimulation. The effects of different doses on the blood viscosity of blood stasis model rats were observed. The rats were randomly divided into 6 groups: blank control group (no model), model group, positive control group, high, middle and low dose group. The whole blood viscosity and plasma viscosity were detected by blood viscosity instrument. Compared with the blank group, model group, high shear, low shear whole blood viscosity and plasma viscosity were significantly increased, TT PT significantly shortened, APTT was significantly prolonged, FIB increased significantly, indicating that the model was successful. Compared with the model group, can significantly reduce the Naoluotong group (cut, low cut). Qingnaopian high dose group (low cut), middle dose group (cut, low shear blood viscosity) (P<0.01), Can significantly reduce Naoluotong qingnaopian group, high dose group (P<0.01), plasma viscosity decreased qingnaopian plasma viscosity in low dose group (P<0.05). Conclusion: qingnaopian could improve the blood rheology of blood stasis mice abnormal index, decrease the blood viscosity, blood stasis has certain hemostatic effect.
机译:建立肾上腺素(ADR)皮下注射和冰浴刺激的血瘀模型。观察到不同剂量对血瘀模型大鼠血液粘度的影响。将大鼠随机分为6组:空白对照组(无模型),模型组,阳性对照组,高,中低剂量组。通过血液粘度仪检测全血粘度和血浆粘度。与空白组,模型组,高剪切,低剪切全血粘度和血浆粘度明显增加,TT PT显着缩短,ApTt显着延长,FIB显着增加,表明该模型成功。与模型组相比,可以显着减少Naoluotong组(切割,低切割)。青年高剂量组(低切割),中剂量组(切割,低剪切血液粘度)(P <0.01),可显着降低Naoluotong青春代组,高剂量组(P <0.01),等离子体粘度降低了清爽的血浆粘度低剂量组(P <0.05)。结论:清普安可以改善血瘀小鼠异常指数的血液流变学,降低血液粘度,血瘀具有一定的止血效果。

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