Characterization of the 13 cytopathic BVDV strains from mucosal disease cases from a single herd

机译：从单一群中的粘膜病变病例的13个细胞病变BVDV菌株的表征

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Bovine viral diarrhea virus (BVDV) is a positive single-stranded RNA virus belonging to the Pestivirus genus of the Flaviviridae family. BVDV has a wide host range that includes most ruminants. Noncytopathic (ncp) BVDV may establish lifelong persistent infections in calves following infection of the fetus between 40 and 120 days of gestation. Cytopathic (cp) BVDV strains arise from ncp strains via mutations. The most common cp mutations are insertions of RNA derived from either host or a duplicationof viral sequences into the region of the genome coding for the NS2/3 protein. Superinfection of a persistently infected animal with a cp virus can give rise to mucosal disease (MD), a condition that is invariably fatal.

机译：牛病毒腹泻病毒（BVDV）是属于黄病毒族家族的瘟病毒属的正链RNA病毒。 BVDV具有广泛的主机范围，包括大多数反刍动物。非骨盆（NCP）BVDV可以在妊娠40至120天的胎儿感染后确定犊牛的终身持续感染。通过突变从NCP菌株产生细胞病变（CP）BVDV菌株。最常见的CP突变是从宿主或病毒序列重复的RNA插入到NS2 / 3蛋白的基因组区域的区域中。具有CP病毒的持续受感染的动物的SuperInfection可以引起粘膜疾病（MD），这种病症总是致命的。

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《Annual Conference of the American^Association^of^Bovine^Practitioners., Conference》|2014年||共2页
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M.F. Darweesh; M.K.S. Rajput; L.J. Braun; J.D. Neill; J.F. Ridpath; C.C.L. Chase;
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1. Characterization of the cytopathic BVDV strains isolated from 13 mucosal disease cases arising in a cattle herd [J] . Darweesh Mahmoud F., Rajput Mrigendra K. S., Braun Lyle J., Virus Research: An International Journal of Molecular and Cellular Virology . 2015,第Null期

机译：从牛群中发生的13例粘膜疾病病例中分离出的细胞性BVDV菌株的特征
2. Induction of Mucosal Disease in Cattle Persistently Infected with Noncytopathic Bovine Viral Diarrhea-Mucosal Disease Virus by Superinfection with Cytopathic Bovine Viral Diarrhea-Mucosal Disease Virus [J] . Kazuo KODAMA, Keizou TAKAMURA, Kentaro KAWAZU, The Journal of Veterinary Medical Science . 1993,第1期

机译：通过细胞感染性牛病毒性腹泻-粘膜病病毒的过度感染诱导持续感染非细胞性牛病毒性腹泻-粘膜病病毒的牛的粘膜病
3. Cytopathic BVDV-1 strain induces immune marker production in bovine cells through the NF-kappaB signaling pathway [J] . Ferna Fredericksen, Gonzalo Carrasco, Melina Villalba, Molecular Immunology . 2015,第2aPta1期

机译：细胞病性BVDV-1株通过NF-κB信号通路诱导牛细胞中免疫标记物的产生
4. Characterization of the 13 cytopathic BVDV strains from mucosal disease cases from a single herd [C] . M.F. Darweesh, M.K.S. Rajput, L.J. Braun, Annual Conference of the American^Association^of^Bovine^Practitioners., Conference . 2014

机译：从单一群中的粘膜病变病例的13个细胞病变BVDV菌株的表征
5. Identification and characterization of TNFR-like receptors for subgroups B, D, and E avian leukosis viruses: Two isoforms of a common receptor explain non-reciprocal receptor interference between cytopathic and non-cytopathic avian retroviruses. [D] . Adkins, Heather Breen. 2000

机译：B，D和E组禽类白血病病毒的TNFR样受体的鉴定和特征：共同受体的两种同工型解释了细胞性和非细胞性禽逆转录病毒之间的不可逆受体干扰。
6. Estimation of Herd Incidence of Infection with Bovine Virus Diarhoea Virus (BVDV) in Herds Previously without Animals Persistently Infected with BVDV [O] . H. Houe, V. Palfi 1993

机译：估计牛病毒腹泻病毒（BVDV）在以前没有动物持续感染BVDV的动物的牛粪病毒（BVDV）的估算
7. Induction of Mucosal Disease in Cattle Persistently Infected with Noncytopathic Bovine Viral Diarrhea-Mucosal Disease Virus by Superinfection with Cytopathic Bovine Viral Diarrhea-Mucosal Disease Virus. [O] . Nagaaki NAKAJIMA, Shin-ichi FUKUYAMA, Tadashi HIRAHARA, 1993

机译：用细胞因素牛病毒腹泻粘膜病病毒诱导牛持续感染的丧道丧失感染的牛持续感染的丧工伴随着无骨疗法牛病毒腹泻病毒。
8. Genetic Transfer of a Mucosal Adherence Factor (R1) from an Enteropathogenic Escherichia coli Strain Into a Shigella flexneri Strain and the Phenotypic Suppression of this Adherence Factor. [R] . Cheney, C. P., Formal, S. B., Schad, P. A., 1983

机译：粘膜粘附因子（R1）从肠致病性大肠杆菌菌株遗传转移到福氏志贺菌菌株和该粘附因子的表型抑制。

Characterization of the 13 cytopathic BVDV strains from mucosal disease cases from a single herd

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