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首页> 外文会议>International Conference on Social Science, Education Management and Sports Education >Effects of Total Flavonoids of Epimedium in Climacteric Model Rats
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Effects of Total Flavonoids of Epimedium in Climacteric Model Rats

机译：总黄酮类异己总黄酮在更年期模型大鼠中的影响

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Objective: To investigate the effects of Total Flavonoids of Epimedium (TFE) in climacteric model rats. Method: Utilized castration method to make climacteric syndrome animal model and observed the effects of high middle and low doses of TFE (that is TFE-HD/TFE-MD/TFE-LD) on organ index, serum sex hormone, serum IL-2, BGP content in climacteric rats. Results: Compared with the blank group, the uterus index, spleen index and the level of serum E2, serum IL-2 and BGP levels of model group were significantly decreased (P<0.01), LH, FSH levels were significantly increased (P<0.01). Explained the incomplete removal of the ovaries rat model of climacteric appeared atrophy of spleen and uterus, sex hormone disordered and reduced the immunity and bone calcium. Compared with the model group, each treatment group could significantly increase the spleen index, TFE-MD could significantly improve the uterus index (P<0.05), TFE-HD could significantly improve the uterus index (P<0.01). The TFE in each dosage group and soybean isoflavones (SI) group could significantly increase the level of serum E2(P<0.01), TFE-HD and SI could significantly decrease the serum LH level, TFE-HD could significantly decrease the levels of FSH (P<0.01). Gengnian'an capsule group and TFE-HD were significantly increase serum IL-2 level; SI significantly increased serum BGP level, other each group could significantly increase the level of serum BGP. Conclusion: TFE had significant effect on the treatment of climacteric syndrome.
机译：目的：探讨淫羊藿（TFE）总黄酮类化合物在更年期模型大鼠的影响。方法：利用阉割方法进行更年性综合征动物模型，观察高中和低剂量TFE（即TFE-HD / TFE-MD / TFE-LD）对器官指数，血清性激素，血清IL-2的影响，中小性大鼠的BGP含量。结果：与空白组相比，子宫索引，脾脏指数和血清E2，血清IL-2和BGP水平的模型组的水平显着降低（P <0.01），LH，FSH水平显着增加（P < 0.01）。解释了不完全去除卵巢大鼠血液和子宫萎缩的萎缩，性激素紊乱和降低免疫和骨钙。与模型组相比，每个治疗组可显着增加脾指数，TFE-MD可显着改善子宫指数（P <0.05），TFE-HD可以显着改善子宫指数（P <0.01）。每种剂量组和大豆异黄酮（Si）组中的TFE可以显着增加血清E2的水平（P <0.01），TFE-HD和Si可以显着降低血清LH水平，TFE-HD可以显着降低FSH的水平（P <0.01）。 Gengnian'an胶囊组和TFE-HD显着增加血清IL-2水平; SI显着增加血清BGP水平，其他每组可显着增加血清BGP水平。结论：TFE对综合治疗具有显着影响。

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