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EFFECTS OF DIETARY MACRONUTRIENT CONTENT AND FEEDING PATTERN ON LEPTIN CONCENTRATIONS IN LEAN HEALTHY CATS

机译:膳食Macronutient含量和饲养模式对瘦健康猫瘦素浓度的影响

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Excessive weight gain is associated with metabolic and hormonal changes that predispose cats to insulin resistance and other disorders. The adipokine leptin is an important regulator of energy metabolism, and circulating leptin concentrations correlate with fat mass in cats and other species. In cats, leptin is associated with insulin resistance, independent of bodyweight. Although dietary factors such as energy density, fat content and feeding pattern increase the risk of obesity, there is limited information on how dietary factors such as feeding, fasting, and macronutrient content influence leptin concentrations in cats. The aims of this study were to compare leptin concentrations in lean, healthy cats fed diets high in protein, fat and carbohydrate, to assess associations between leptin concentrations and insulin, glucose, and NEFA concentrations, and to determine the effects of feeding pattern on baseline and postprandial leptin concentrations.
机译:体重增加过度增益与代谢和激素变化有关,使胰岛素抗性和其他疾病易受抗体。 Adipokine Leptin是能量代谢的重要调节剂,循环瘦素浓度与猫和其他物种中的脂肪肿块相关。在猫中,瘦素与胰岛素抵抗有关,与体重无关。虽然能量密度,脂肪含量和饲养模式等饮食因素增加了肥胖的风险,但有关饲料,禁食和Macronutrient含量的膳食因素如何影响猫类中瘦素浓度的有限信息。本研究的目的是将瘦蛋白浓度与蛋白质,脂肪和碳水化合物高饮食中的瘦肉,健康的猫体,以评估瘦素浓度和胰岛素,葡萄糖和Nefa浓度之间的关联,并确定喂养模式对基线的影响和餐后瘦素浓度。

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