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首页> 外文会议>World Congress on Biosensors >Highly sensitive electrospun multiwalled carbon nanotubes embedded zinc oxide nanowire based interface for label free biosensing
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Highly sensitive electrospun multiwalled carbon nanotubes embedded zinc oxide nanowire based interface for label free biosensing

机译：高敏感的电纺碳纳米管嵌入式氧化锌纳米线的界面，用于标签无生物溶解

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We demonstrate synthesis of Multiwalled carbon nanotubes (MWCNTs) embedded highly oriented Zinc Oxide (ZnO) nanowires targeted towards development of ultrasensitive electrochemical nanobiosensors using electrospinning method. The synthesized composite nanowires combines advantages of ZnO such as biocompatibility, electrostatic affinity towards biomolecules with the excellent conductivity and surface functionalization capabilities of MWCNTs. Calcination temperature is optimized so as to ensure MWCNTs are present in their original form and at the same time highly crystalline ZnO is obtained. The key advantage of this process is that there is no separate functionalization process is required to create functional groups on MWCNTs. Furthermore, the electrochemical activity of MWCNTs embedded ZnO nanowires is much higher as compared to pure ZnO nanowires. We have demonstrated the performance of electrochemical nanobiosensor using Biotin-streptavidin interaction as model system. The sensor exhibits excellent sensitivity in the range 10 μgmL~(-1)-0.5 fgmL~(-1) of streptavidin with 0.5fgmL~(-1) limit of detection.
机译：我们证明嵌入目标朝向使用静电纺丝法超灵敏电化学纳米生物传感器的发展高度取向的氧化锌（ZnO）的纳米线多壁碳纳米管（MWCNT）的合成。 ZnO的合成的复合纳米线联合机的优点，例如生物相容性，朝与多壁碳纳米管的优异的导电性和表面官能化的生物分子的能力静电的亲和力。煅烧温度被优化，以确保多壁碳纳米管存在于它们的原始形式，并在得到高度结晶的ZnO的同时。这个过程的主要优点是，有没有需要单独的官能化方法对多壁碳纳米管制作的官能团。此外，嵌入的ZnO纳米线多壁碳纳米管的电化学活性是相对于纯的ZnO纳米线作为高得多。我们已经证明了使用生物素 - 链霉亲交互模型系统电化学纳米生物传感器的性能。该传感器表现出与0.5fgmL〜（-1）检测限链菌素的范围10μgmL〜（-1）-0.5 fgmL〜（-1）优异的灵敏度。

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