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Measurement of the nonmagnetic coating thickness of core-shell magnetic nanoparticles by controlled magnetization magnetic force microscopy

机译:通过控制磁化磁力显微镜测量芯壳磁性纳米粒子的非磁性涂层厚度

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Magnetic nanoparticles (MNPs) represent an interesting tool for several biomedical applications. In order to improve the dispersion stability, the biocompatibility and bio-functionality, MNPs need to be coated with non-magnetic films. The optimization of these systems requires the deep characterization not only of the magnetic core, but also of the coating features. Beside the chemical and physical properties of the coating, its thickness is another important property which can influence the size, the shape and the overall magnetic behavior of the NPs system. In this work we propose a possible method to measure the thickness of the non-magnetic coating of core-shell MNPs through the use of controlled magnetization-magnetic force microscopy (CM-MFM). A preliminary study on the applicability of the proposed method has been performed on Fe_3O_4 NPs coated with a Cu film.
机译:磁性纳米颗粒(MNP)代表几种生物医学应用的有趣工具。为了提高分散稳定性,生物相容性和生物官能团,MNP需要涂覆有非磁性膜。这些系统的优化不仅需要磁芯的深度表征,还需要涂层特征。除了涂层的化学和物理性质旁边,其厚度是可以影响NPS系统的尺寸,形状和整体磁力的另一个重要性质。在这项工作中,我们提出了一种可能的方法,通过使用受控的磁化 - 磁力显微镜(CM-MFM)来测量核心壳MNP的非磁性涂层的厚度。对涂有Cu膜的Fe_3O_4 NPS进行了对所提出的方法的适用性的初步研究。

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