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Research Status and Development Trend of The Signal Pathway of Allergic Asthma

机译：过敏性哮喘信号途径的研究现状及发展趋势

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Allergic asthma is a chronic airway inflammatory disease characterized by the infiltration of eosinophils in the lungs and the production of various kinds of stimulating factors, incidence rate showed an upward trend. In this paper, the research status and future development trend of the signal pathway of allergic asthma were introduced. The recombinant allergen vaccine DCP-IhC-ProDerflof 1 kinds of allergen PrDerfl in the experiment is put forward, which is used to investigate the effect of specific immunotherapy on the vaccine specific immunotherapy and the related pathway PI3K/AKT in asthmatic mice. Pathway mechanism provides a new idea for specific immunotherapy of allergic asthma caused by dust mites, which has a certain theoretical significance and clinical application value, and may be a new promising approach for the treatment of allergic asthma.
机译：过敏性哮喘是一种慢性气道炎性疾病，其特征在于肺部肺嗜酸性粒细胞渗透和各种刺激因素的产生，发病率显示出趋势。 本文介绍了过敏性哮喘信号途径的研究现状和未来发展趋势。 提出了重组过敏原疫苗DCP-IHC-PREDERFLOF在实验中的1种过敏原PRDERFL，用于探讨特定免疫疗法对哮喘小鼠疫苗特异性免疫疗法和相关途径PI3K / AKT的影响。 途径机制为灰尘螨虫引起的过敏性哮喘的特定免疫疗法提供了一种新的思路，具有一定的理论意义和临床应用价值，并且可能是治疗过敏性哮喘的新有希望的方法。

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