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首页> 外文会议>International Scientific Conference "New Operational Technologies" >Long-Term Clinical Results of Autologous Bone Marrow Cd 133+ Cell Transplantation in Patients with St-Elevation Myocardial Infarction
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Long-Term Clinical Results of Autologous Bone Marrow Cd 133+ Cell Transplantation in Patients with St-Elevation Myocardial Infarction

机译：ST升高心肌梗死患者自体骨髓CD 133+细胞移植的长期临床结果

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摘要

The aim of the study was investigate the long-term results of autologous bone marrow CD 133+ cell transplantation in patients with primary ST-Elevation Myocardial Infarction (STEMI). Methods and results: From 2006 to 2007, 26 patients with primary STEMI were included in an open randomized study. Patients were randomized to two groups: 1 st - included patients underwent PCI and transplantation of autologous bone marrow CD 133+ cell (n= 10); 2nd - patients with only PCI (n= 16). Follow-up study was performed 7.70+0.42 years after STEMI and consisted in physical examination, 6-min walking test, Echo exam. Total and cardiovascular mortality in group 1 was lower (20% (n= 2) vs. 44% (n= 7), p= 0.1 and 22% (n= 2) vs. 25% (n =4), (p=0.53), respectively). Analysis of cardiac volumetric parameters shows significant differences between groups: EDV of 100.7 ± 50.2 mL vs. 144.40±42.7 mL, ESV of 56.3 ± 37.8 mL vs. 89.7 ± 38.7 mL in 1st and 2nd groups, respectively. Data of the study showed positive effects of autologous bone marrow CD 133+ cell transplantation on the long-term survival of patients and structural status of the heart.
机译：该研究的目的是研究初级ST升高心肌梗死患者（STEMI）的自体骨髓CD 133+细胞移植的长期结果。方法和结果：从2006年到2007年，患有26例初级症患者均包含在开放的随机研究中。患者随机分为两组：1名患者接受了PCI和自体骨髓CD 133+细胞的移植（n = 10）;二 - 只有PCI的患者（n = 16）。在STEMI后进行7.70 + 0.42年进行后续研究，并在体检，6分钟步行测试，回声检查。第1组的总和心血管死亡率较低（20％（n = 2）vs.4％（n = 7），p = 0.1和22％（n = 2）与25％（n = 4），（p分别= 0.53）。心脏体积参数分析显示，分别为100.7±50.2ml的eDV之间的显着差异，分别为144.40±42.7ml，ESV为89.7±37.8ml，在第1和第2组中的89.7±38.7ml。该研究的数据显示了自体骨髓CD 133+细胞移植对患者长期存活的积极影响和心脏的结构状态。

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