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Standardized Morbidity Ratio for Leptospirosis Mapping in Malaysia

机译:马来西亚钩纹血管区测定的标准化发病率

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Leptospirosis is a worldwide zoonotic disease that affects human health in many parts of the world including Malaysia. Leptospirosis is a disease caused by the infection of pathogenic Leptospira genus called Spirochaetes. Leptospirosis can be transmitted directly or indirectly from rats to human. The human infection is usually caused by human contact with urine or tissues of infected animal. This disease can be spread through mucus membrane such as mouth, nose and eyes, ingestion of contaminated food and water and also exposed injured skin to contaminated water or soil. There is still no vaccine currently available for the prevention or treatment of leptospirosis disease but this disease can be treated if it is diagnosed early. Therefore, the aim of this study is to estimate the relative risk for leptospirosis disease based initially on the most common statistic used in the study of disease mapping called Standardized Morbidity Ratio (SMR). We then apply SMR to leptospirosis data obtained in Malaysia. The results show that the states of Melaka have very high risk areas. The states of Kedah, Terengganu and Kelantan are identified as high risk areas. The states of Perak, Perlis, Sabah and Sarawak showed medium risk areas. This is followed by low risk by other states except Pahang, Johor and Labuan with very low risk areas. In conclusion, SMR method is the best method for mapping leptospirosis because by referring to the relative risk maps, the states that deserve closer look and disease prevention can be identified.
机译:钩端螺旋体病是一种全球性的动物园疾病,这些疾病会影响世界许多地区的人类健康,包括马来西亚。钩端螺旋体是一种由致病性百叶菌属的感染引起的疾病,称为螺旋体。钩端螺旋体病可以直接或间接地从大鼠传播。人类感染通常是由人类接触与感染动物的尿液或组织引起的。这种疾病可以通过粘膜,鼻子和眼睛,摄入污染的食物和水中,并将受伤的皮肤暴露于受污染的水或土壤。目前仍然没有疫苗可用于预防或治疗钩螺旋体病症,但如果早期诊断,可以治疗这种疾病。因此,本研究的目的是估算最初基于疾病映射研究中最常见的统计数据的胸膜血管疾病疾病的相对风险,称为标准化发病率(SMR)。然后,我们将SMR应用于马来西亚获得的乳化梭菌数据。结果表明,马六甲的州风险地区具有很高的风险地区。 Kedah,Terengganu和Kelantan的州被确定为高风险领域。 Perak,Perlis,Sabah和Sarawak的州展示了中等风险地区。除了彭亨,柔佛和柔和地区,其他州的其他州的风险很低。总之,SMR方法是映射钩端螺旋体症的最佳方法,因为通过参考相对风险地图,可以识别应得更仔细的外观和疾病预防的状态。

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