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首页> 外文会议>Meeting of the Electrochemical Society;International Meeting on Chemical Sensors >Exhaled Breath Analysis for Assessment of IBD (Inflammatory Bowel Disease) Based on Electronic Nose System
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Exhaled Breath Analysis for Assessment of IBD (Inflammatory Bowel Disease) Based on Electronic Nose System

机译：基于电子鼻系统的IBD（炎症性肠疾病）评估的呼气呼气分析

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The diagnosis and differentiation of IBD (Inflammatory Bowel Disease) lacks a single gold standard. IBD commonly suffers from a delay in time from first occurrence of symptoms to diagnosis, especially in young patients with ileal disease, which hinders our ability to alter the progression of disease. Also, once the diagnosis of IBD is made its sub categorization into CD (Crohn's Disease) or UC (ulcerative colitis) is critical for determining the optimal treatment strategy. It is important to identify at risk population that could benefit from a therapeutic approach. Metabolomics studies have recently enter the field of IBD. A variety of studies have been conducted to be significantly different between CD, UC and heathy controls. Limitation for use of metabolomics markers would be too time-consuming and expensive for assessment of IBD or invasive testing in cases. An ideal approach regarding IBD assessment is that breath metabolome offers great potential with simply, easy to use, non-invasive, cheap, rapid and reproducible. An electronic nose system, which is an instrument comprises an array of chemical sensors with partial specificity and an appropriate pattern recognition system capable of recognition simple or complex odors, has been suggested a potential alternative as a novel approach for breath analytic technique.
机译：IBD（炎症性肠疾病）的诊断和分化缺乏单一的金标准。 IBD通常患有延迟从第一次出现症状到诊断，特别是在患有髂骨疾病的年轻患者中，阻碍了我们改变疾病进展的能力。此外，一旦IBD的诊断被分类为CD（CROHN疾病）或UC（溃疡性结肠炎）对于确定最佳治疗策略至关重要。重要的是要识别可能从治疗方法中受益的风险群体。代谢组学研究最近进入了IBD领域。在CD，UC和Heathy对照之间进行了各种研究是显着差异。使用代谢物标记的限制对于评估IBD或侵入性测试时，可以过于耗时和昂贵。关于IBD评估的理想方法是，呼吸代谢物简单，易用，无侵入性，便宜，快速和可重复提供了极大的潜力。作为仪器的电子鼻系统包括具有部分特异性的化学传感器和能够识别简单或复杂的气味的适当图案识别系统，已经提出了一种潜在的替代作为呼吸分析技术的新方法。

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