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首页> 外文会议>Conference on photons plus ultrasound: imaging and sensing >A Suite of Phantom-Based Test Methods for Assessing Image Quality of Photoacoustic Tomography Systems
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A Suite of Phantom-Based Test Methods for Assessing Image Quality of Photoacoustic Tomography Systems

机译：基于幻影的幻像测试方法套件，用于评估光声断层扫描系统的图像质量

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As Photoacoustic Tomography (PAT) matures and undergoes clinical translation, objective performance test methods are needed to facilitate device development, regulatory clearance and clinical quality assurance. For mature medical imaging modalities such as CT, MRI, and ultrasound, tissue-mimicking phantoms are frequently incorporated into consensus standards for performance testing. A well-validated set of phantom-based test methods is needed for evaluating performance characteristics of PAT systems. To this end, we have constructed phantoms using a custom tissue-mimicking material based on PVC plastisol with tunable, biologically-relevant optical and acoustic properties. Each phantom is designed to enable quantitative assessment of one or more image quality characteristics including 3D spatial resolution, spatial measurement accuracy, ultrasound/PAT co-registration, uniformity, penetration depth, geometric distortion, sensitivity, and linearity. Phantoms contained targets including high-intensity point source targets and dye-filled tubes. This suite of phantoms was used to measure the dependence of performance of a custom PAT system (equipped with four interchangeable linear array transducers of varying design) on design parameters (e.g., center frequency, bandwidth, element geometry). Phantoms also allowed comparison of image artifacts, including surface-generated clutter and bandlimited sensing artifacts. Results showed that transducer design parameters create strong variations in performance including a trade-off between resolution and penetration depth, which could be quantified with our method. This study demonstrates the utility of phantom-based image quality testing in device performance assessment, which may guide development of consensus standards for PAT systems.
机译：光声断层成像（PAT）的成熟和经过临床翻译，需要客观性能测试方法，以方便设备的发展，监管部门的批准和临床质量保证。对于成熟的医学成像模式，如CT，MRI和超声，组织模拟幻像经常纳入合成标准以进行性能测试。评估PAT系统的性能特征需要一种良好验证的基于幻像的测试方法。为此，我们使用基于PVC Plastisol的自定义组织模拟材料构成了杂色，具有可调谐，生物相关的光学和声学性质。每个幻像都旨在实现一个或多个图像质量特征的定量评估，包括3D空间分辨率，空间测量精度，超声/ PAT共同登记，均匀性，穿透深度，几何失真，灵敏度和线性度。幽灵含有靶标，包括高强度点源靶和染料填充管。这种幻影套件用于测量定制PAT系统的性能的依赖性（配备有四个不同设计的可互换线性阵列换能器的设计参数（例如，中心频率，带宽，元素几何）。幽灵还允许比较图像伪像，包括表面产生的杂波和带状传感伪像。结果表明，换能器设计参数在分辨率和穿透深度之间产生强大的性能变化，包括分辨率和渗透深度之间的权衡，这可以通过我们的方法量化。本研究表明，在设备性能评估中，幻影的图像质量测试的效用可能导致开发PAT系统的共识标准。

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