The Penetration and Movement of Nanoparticles on Membrane

机译：纳米颗粒对膜的渗透和运动

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In this study, we used GROMACS, a versatile package for performing molecular dynamics to simulate the interactions between different nanoparticles and Dipalmitoyl PhosPhatidyl Choline (DPPC) to understand the physical mechanisms that govern the interactions between nanoparticles and lipid membrane. Our simulations show the responses of the lipid bilayer to the nanoparticles, including the formation of an adsorbent layer on the nanoparticle surface, transmembrane ectopic movements and inconspicuous endocytosis of the nanoparticle by the membrane. Effects of the size of the nanoparticles, structural shape and charge state on the interaction and transport processes will be examined and summarized.

机译：在这项研究中，我们使用Gromacs，一种用于进行分子动力学的多功能包装，用于模拟不同纳米颗粒和二普利磷脂酰胆碱（DPPC）之间的相互作用，以了解控制纳米颗粒和脂质膜之间相互作用的物理机制。我们的模拟显示脂质双层对纳米颗粒的反应，包括在纳米颗粒表面上形成吸附剂层，膜异位运动和膜通过膜的不显眼的内吞作用。纳米颗粒的尺寸，结构形状和电荷状态对相互作用和运输过程的影响将被检查和总结。

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《Conference on reporters, markers, dyes, nanoparticles, and molecular probes for biomedical applications》|2020年|vii v. p.|共11页
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作者
Lianxin Xin; Zixuan Wang; Jian Zhao; Zachary Tyler; Hacene Boukari; Essaid Zerrad; Jun Ren;
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中图分类生物医学工程;
关键词
Gold Nanoparticles; DPPC; Cell Membrane; GROMACS; Molecular Dynamics;

机译：金纳米颗粒;DPPC;细胞膜;Gromacs;分子动力学;

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1. Membrane-Potential-Induced Electroporation as a Physical Mechanism for Metal Nanoparticle Penetration through a Cell Membrane [J] . Ulberg Z. R., Shilov V. N. Colloid journal . 2014,第6期

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2. Arginine-Terminated Nanoparticles of < 10 nm Size for Direct Membrane Penetration and Protein Delivery for Straight Access to Cytosol and Nucleus [J] . Panja Prasanta, Jana Nikhil R. Journal of physical chemistry letters . 2020,第6期

机译：用于直接膜渗透和蛋白质递送的精氨酸封端的纳米颗粒，用于直接进入细胞溶质和核
3. Conformational-transited protein corona regulated cell-membrane penetration and induced cytotoxicity of ultrasmall Au nanoparticles [J] . Yang Huayan, Wang Meng, Zhang Yanmin, RSC Advances . 2019,第8期

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4. The Penetration and Movement of Nanoparticles on Membrane [C] . Lianxin Xin, Zixuan Wang, Jian Zhao, Conference on reporters, markers, dyes, nanoparticles, and molecular probes for biomedical applications . 2020

机译：纳米颗粒在膜上的渗透和运动
5. STUDIES OF CHOLESTEROL IN BIOLOGICAL MEMBRANES: DISTRIBUTION AND TRANSBILAYER MOVEMENT OF CHOLESTEROL IN MYCOPLASMA MEMBRANES, AND INTERACTION BETWEEN PHOSPHATIDYLCHOLINE ANALOGS AND CHOLESTEROL IN ARTIFICIAL BILAYER MEMBRANES. [D] . CLEJAN, SANDA Z. 1979

机译：生物膜中胆固醇的研究：髓鞘膜中胆固醇的分布和转移运动，以及人工双层膜中磷脂酰胆碱类似物和胆固醇之间的相互作用。
6. Surface Structure-Regulated Cell Membrane Penetration by Monolayer Protected Nanoparticles [O] . Ayush Verma, Oktay Uzun, Yuhua Hu, -1

机译：单层保护的纳米粒子的表面结构调节细胞膜渗透。
7. Conformational-transited protein corona regulated cell-membrane penetration and induced cytotoxicity of ultrasmall Au nanoparticles [O] . Huayan Yang, Meng Wang, Yanmin Zhang, 2019

机译：构象过渡的蛋白质电晕调节的细胞膜膜渗透和诱导超γA纳米粒子的细胞毒性

The Penetration and Movement of Nanoparticles on Membrane

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