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首页> 外文会议>Conference on Optical Coherence tomography and coherence domain optical methods in biomedicine >Lateral Resolution Enhancement via Imbricated Spectral Domain Optical Coherence Tomography in a Maximum-a-Posterior Reconstruction Framework
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Lateral Resolution Enhancement via Imbricated Spectral Domain Optical Coherence Tomography in a Maximum-a-Posterior Reconstruction Framework

机译：通过横向分辨率通过颠覆谱域光学相干断层扫描在最大 - 后重建框架中提升

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摘要

The lateral resolution of a Spectral Domain Optical Coherence Tomography (SD-OCT) image is limited by the focusing properties of the OCT imaging probe optics, the wavelength range which SD-OCT system operates at, spherical and chromatic aberrations induced by the imaging optics, the optical properties of the imaged object, and in the special case of in-vivo retinal imaging by the optics of the eye. This limitation often results in challenges with resolving fine details and structures of the imaged sample outside of the Depth-Of-Focus (DOF) range. We propose a novel technique for generating Laterally Resolved OCT (LR-OCT) images using OCT measurements acquired with intentional imbrications. The proposed, novel method is based on a Maximum A Posteriori (MAP) reconstruction framework which takes advantage of a Stochastic Fully Connected Conditional Random Field (SFCRF) model to compensate for the artifacts and noise when reconstructing a LR-OCT image from imbricated OCT measurement. The proposed lateral resolution enhancement method was tested on synthetic OCT measurement as well as on a human cornea SD-OCT image to evaluate the usefulness of the proposed approach in lateral resolution enhancement. Experimental results show that applying this method to OCT images, noticeably improves the sharpness of morphological features in the OCT image and in lateral direction, thus demonstrating better delineation of fine dot shape details in the synthetic OCT test, as well as better delineation of the keratocyte cells in the human corneal OCT test image.
机译：光谱域光学相干断层扫描（SD-OCT）图像的横向分辨率受OCT成像探针光学元件的聚焦性质的限制，SD-OCT系统在成像光学诱导的球形和色差下操作的波长范围，成像对象的光学性质，以及眼睛光学器件的体内视网膜成像的特殊情况。这种限制往往导致挑战在焦点深度（DOF）范围之外的成像样品的细节和结构的挑战。我们提出了一种新颖的技术，用于使用具有故意虚设的OCT测量来产生横向分辨的OCT（LR-OCT）图像。该提出的新方法基于最大的后验（MAP）重建框架，该框架利用随机完全连接的条件随机场（SFCRF）模型来补偿伪像和噪声，当从覆层OCT测量重建LR-OCT图像时。所提出的横向分辨率增强方法在合成的OCT测量以及人角膜SD-OCT图像上进行测试，以评估所提出的方法在横向分辨率增强中的有用性。实验结果表明，将该方法应用于OCT图像，显着提高了OCT图像和横向的形态特征的锐度，从而展示了合成OCT试验中的细圆点细节的更好描绘，以及更好地描绘了角蛋白酶人角膜OCT测试图像中的细胞。

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