• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>Conference on vaccine technology VI >USING THE AdVac? VACCINE MANUFACTURING PLATFORM FOR RAPID RESPONSE TO INFECTIOUS DISEASE OUTBREAKS
【24h】

USING THE AdVac? VACCINE MANUFACTURING PLATFORM FOR RAPID RESPONSE TO INFECTIOUS DISEASE OUTBREAKS

机译：使用advac？疫苗制造平台，用于快速反应传染病爆发

获取原文
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

In the last decade, we have seen several examples of new or existing infectious diseases that rapidly developed into epidemics with devastating effects and sometimes high mortality. In order to combat these threats and to be prepared for future epidemics, it is essential to develop and produce vaccines against these pathogens. A lesson that can be learned from the recent Ebola epidemic in Western Afrika is that speed at which vaccines are developed is essential. A flexible and robust manufacturing platform can play a vital role in meeting the pressing timelines. At Janssen vaccines, we have developed a drug substance manufacturing platform based on AdVac? and PerC6? technology. This platform is able to handle significant variations that are associated with the production of different vaccine candidates while maintaining a consistent quality of the end product. Furthermore, the platform process is fast, low-footprint, high yield and cost-effective. The platform nature allows for quick incorporation of new vaccine candidates into our manufacturing pipeline with minimal time required for development and with fast and smooth technology transfers between development and GMP manufacturing, since experience, equipment, documentation, analytical methods can be efficiently leveraged between candidates. In this presentation, we will demonstrate the value of the AdVac? manufacturing platform for the prevention and combating of rapidly emerging epidemics of infectious diseases.
机译：在过去十年中，我们已经看到了几种新的或现有的传染病的例子，这些疾病迅速发展成具有毁灭性效果和有时高死病的流行病。为了打击这些威胁并为未来的流行病做好准备，必须为这些病原体开发和生产疫苗。可以从最近的西非AFRIWA中从最近的埃博拉流行病学中学到的课程是疫苗所产生的速度至关重要。灵活且强大的制造平台可以在满足按压时间表来发挥重要作用。在Janssen疫苗，我们开发了基于Advac的药物制造平台？和perc6？技术。该平台能够处理与不同疫苗候选的产生相关的显着变化，同时保持最终产品的一致质量。此外，平台过程快速，低占地面积，高产率高，成本效益。平台性质可以快速将新的疫苗候选人纳入我们的制造管道，并在开发所需的时间内和开发和GMP制造之间的快速和光滑的技术转移，因为经验，设备，文档，分析方法可以有效地利用候选者。在这个演示中，我们将展示Advac的价值？预防传染病快速新兴流行病的制造平台。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号