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Optimization of vaccine delivery operations with regional distribution centers

机译：利用区域分布中心优化疫苗送货业务

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Vaccines save millions of lives each year. However, there are challenges such as supply shortages and unreliable transportation and storage facilities in the developing countries that affect patients' access and, availability and quality of the vaccines. Many of the developing countries do not have the resources to design and manage a temperature-controlled (cold chain) supply chains and may consider using other storage devices that do not depend on unreliable electric power. We propose a mixed-integer programming model to optimize the delivery of vaccines to the developing countries in Africa. Our model considers usage of regional distribution centers that can serve as more reliable storage facilities and distribute vaccines to other countries that may not be able to properly manage and distribute vaccines. Our model aims to find the locations of the regional distribution centers (RDCs), optimal allocation of countries to RDCs and transportation modes to be used considering capacity and expiration duration based-on cold-chain life.
机译：疫苗每年节省数百万个生命。但是，在发展中国家的供应短缺和不可靠的运输和储存设施（如疫苗）的供应短缺和不可靠的运输和储存设施，以及疫苗的可用性和质量，存在挑战。许多发展中国家都没有资源设计和管理温度控制（冷链）供应链，并且可以考虑使用不依赖于不可靠电力的其他存储设备。我们提出了一种混合整数的编程模型，优化了非洲发展中国家的疫苗。我们的模型考虑了区域分销中心的使用，这些中心可以作为更可靠的储存设施，并将疫苗分发给可能无法适当管理和分配疫苗的其他国家。我们的型号旨在找到区域分销中心（RDC）的地点，以考虑基于冷链寿命的能力和到期时间来使用竞争对手和运输方式。

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