Direct Electrical Detection of Biological Species

机译：直接电检测生物物种

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Suspended-Gate FETs, namely SGFET, with sub-micron gap, is shown to be able to detect biological species with very high sensitivity in a large range of concentration. Examples of detection of DNA (through the DelF508 mutation of the cystic fibrosis gene that is widely disseminating in Europe and North America, and one mutation of BRCA1 gene that is the main indication of the possibility for a woman to have breast cancer) and proteins (through the transferrin that is the only carrier of iron in blood) are presented. This very sensitive electrical detection without any labelling is shown to deliver directly readable signal.

机译：具有亚微米间隙的悬浮门FET（即SGFET）显示出能够在很大的浓度范围内以非常高的灵敏度检测生物物种。 DNA（通过在欧洲和北美广泛传播的囊性纤维化基因的DelF508突变，以及一个BRCA1基因的突变是女性有患乳腺癌的可能的主要征兆）的检测实例和蛋白质（通过运铁蛋白（血液中铁的唯一载体）呈现。这种没有任何标签的非常灵敏的电检测显示为传递直接可读的信号。

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来源
《Microelectronics Technology and Devices-SBMicro 2008》|2008年|3-10|共8页
会议地点 Gramado(BR);Gramado(BR);Gramado(BR);Gramado(BR);Gramado(BR);Gramado(BR)
作者
O. De Sagazan; M. Hamois; A. Girard; F. LeBihan; A.C.Salauen; S. Crand; T. Mohammed-Brahim;
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作者单位

GM-IETR UMR-CNRS 6164, Universite RENNES I, 35042 Rennes Cedex, FRANCE;

GM-IETR UMR-CNRS 6164, Universite RENNES I, 35042 Rennes Cedex, FRANCE;

GM-IETR UMR-CNRS 6164, Universite RENNES I, 35042 Rennes Cedex, FRANCE;

GM-IETR UMR-CNRS 6164, Universite RENNES I, 35042 Rennes Cedex, FRANCE;

GM-IETR UMR-CNRS 6164, Universite RENNES I, 35042 Rennes Cedex, FRANCE;

GM-IETR UMR-CNRS 6164, Universite RENNES I, 35042 Rennes Cedex, FRANCE;

GM-IETR UMR-CNRS 6164, Universite RENNES I, 35042 Rennes Cedex, FRANCE;

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正文语种 eng
中图分类微电子学、集成电路（IC）;
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Direct Electrical Detection of Biological Species

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