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首页> 外文会议>Multiphoton microscopy in the biomedical sciences XVII >Multi-wavelength time-lens source and its application to nonresonant background suppression for coherent anti-Stokes Raman scattering microscopy
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Multi-wavelength time-lens source and its application to nonresonant background suppression for coherent anti-Stokes Raman scattering microscopy

机译：多波长时间透镜源及其在相干抗斯托克斯拉曼散射显微镜非共振背景抑制中的应用

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摘要

We demonstrate a robust, all-fiber, two-wavelength time-lens source for background-free coherent anti-Stokes Raman scattering (CARS) imaging. The time-lens source generates two picosecond pulse trains simultaneously: one at 1064 nm and the other tunable between 1040 nm and 1075 nm (~ 400 mW for each wavelength). When synchronized to a mode-locked Ti:Sa laser, the two wavelengths are used to obtain on- and off-resonance CARS images. Real-time subtraction of the nonresonant background in the CARS image is achieved by the synchronization of the pixel clock and the time-lens source. Background-free CARS imaging of sebaceous glands in ex vivo mouse tissue is demonstrated. Keywords: Ultrafast lasers; Fiber optics sources; Raman microscopy.
机译：我们演示了一个强大的全光纤，两波长时间透镜源，用于无背景相干反斯托克斯拉曼散射（CARS）成像。时间透镜源同时生成两个皮秒脉冲序列：一个在1064 nm，另一个在1040 nm至1075 nm之间可调（每个波长约400 mW）。当与锁模的Ti：Sa激光器同步时，这两个波长将用于获取开和关共振的CARS图像。 CARS图像中非共振背景的实时减法是通过像素时钟和时间透镜源的同步实现的。证明了离体小鼠组织中皮脂腺的无背景CARS成像。关键词：超快激光器光纤源；拉曼显微镜。

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  • 会议地点 San Francisco(US)
  • 作者

    Bo Li; Kriti Charan; Ke Wang; David Sinefeld; Chris Xu;

  • 作者单位

    School of Applied and Engineering Physics, Cornell University, Ithaca, NY, USA 14853;

    School of Applied and Engineering Physics, Cornell University, Ithaca, NY, USA 14853;

    Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen, China 518060;

    School of Applied and Engineering Physics, Cornell University, Ithaca, NY, USA 14853;

    School of Applied and Engineering Physics, Cornell University, Ithaca, NY, USA 14853;

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