Modelling the response of whispering-gallery-mode optical resonators for biosensing applications

机译：为生物传感应用建模耳语画廊模式光谐振器的响应

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We present a theoretical analysis of the response of whispering gallery modes for biosensing applications, studied numerically in microcylinders and semi-analytically in microspheres. The effect of single and multiple particles is calculated, simulating biological analytes of different sizes and polarizabilities attached to the microresonator surface. Besides whispering-gallery-mode frequency shifts, we find that also broadenings and splittings (from lifted rotational symmetry) appear due to particles attachment and/or the vicinity to a planar coupler. For a single analyte, both particle size and refractive index can be determined from the broadening and shift, opening the perspective to a new biosensing modality.

机译：我们提出了耳语回廊模式对生物传感应用响应的理论分析，在微圆柱体中进行了数值研究，在微球体中进行了半解析研究。计算单个和多个粒子的效果，模拟附着在微谐振器表面的不同大小和极化率的生物分析物。除了耳语画廊模式的频移，我们还发现由于粒子的附着和/或与平面耦合器的邻近，也出现了展宽和裂痕（由于旋转对称性的升高）。对于单一分析物，可以通过加宽和移动来确定粒径和折射率，从而为新的生物传感方式打开了视野。

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来源
《Nanoscale imaging, sensing, and actuation for biomedical applications VI》|2009年|71880G.1-71880G.7|共7页
会议地点 San Jose CA(US)
作者
W. Langbein; L. Chantada; N I Nikolaev; A Ivanov; P Borri;
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作者单位

Cardiff University, School of Physics and Astronomy , The Parade, Cardiff CF24 3AA, United Kingdom;

Cardiff University, School of Biosciences, Museum Avenue, Cardiff CF10 3AX, United Kingdom;

Cardiff University, School of Physics and Astronomy , The Parade, Cardiff CF24 3AA, United Kingdom;

Cardiff University, School of Physics and Astronomy , The Parade, Cardiff CF24 3AA, United Kingdom;

Cardiff University, School of Biosciences, Museum Avenue, Cardiff CF10 3AX, United Kingdom;

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原文格式 PDF
正文语种 eng
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关键词
optical biosensors; whispering gallery modes;

机译：光学生物传感器；耳语画廊模式;

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1. Portable Automatic Microring Resonator System Using a Subwavelength Grating Metamaterial Waveguide for High-Sensitivity Real-Time Optical-Biosensing Applications [J] . Soni Varun, Chang Ching-Wen, Xu Xiaochuan, IEEE Transactions on Biomedical Engineering . 2021,第6期

机译：便携式自动微管谐振器系统使用亚波长光栅超材料波导，用于高灵敏度实时光学生物传感器应用
2. Air-band optical resonators in one-dimensional Si photonic crystal waveguides for biosensing applications [J] . Kakuro Hirai, Takahiro Araki, Jingnan Cai, Japanese journal of applied physics . 2014,第4S期

机译：一维Si光子晶体波导中的空气带光学谐振器，用于生物传感应用
3. Association of vertically coupled polymer micro-resonator and phase-sensitive optical low coherence interferometer for label-free biosensing applications [J] . Anne-Francoise Obaton, Yacouba Sanogo, Catherine Yardin, Metrologia: International Journal of Scientific Metrology: = Internationale Zeitschrift fur Wissenschaftliche Metrologie: = Journal International de Metrologie Scientifique . 2014,第1期

机译：垂直耦合聚合物微谐振器与相敏光学低相干干涉仪的结合，可用于无标签生物传感应用
4. Modelling the response of whispering-gallery-mode optical resonators for biosensing applications [C] . Langbein W., Chantada L., Nikolaev N.I., International Conference on Transparent Optical Networks;ICTON '09 . 2009

机译：为生物传感应用建模耳语画廊模式光谐振器的响应
5. Embedded Sensing System for Whispering-Gallery-Mode Optical Resonators [D] . Xu, Xiangyi. 2019

机译：耳语 - 画廊模式光学谐振器的嵌入式传感系统
6. Label-Free Biosensing with High Selectivity in Complex Media using Microtoroidal Optical Resonators [O] . Erol Ozgur, Pelin Toren, Ozan Aktas, -1

机译：使用微环形光学谐振器在复杂介质中具有高选择性的无标记生物传感
7. Guided Wave Resonant Optical Structures and LED Micro Resonators for Biosensing Applications [O] . Rohit Goswami -1

机译：用于生物传感应用的引导波谐振光学结构和LED微谐振器

Modelling the response of whispering-gallery-mode optical resonators for biosensing applications

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