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Symmetries and Biology: a new approach to Biosensing

机译:对称性和生物学:生物传感的新方法

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摘要

We propose a novel detection method based on the symmetry breaking induced by the bio-molecule to be detected. Briefly, by choosing a sensor presenting a particular symmetry, the revolution symmetry, the adsorption of an analyte will break this symmetry. By detecting this change in the symmetries of the system, the presence of bio-molecules can be detected. This optical method provides substantial advantages over current approaches for the conception of biosensors. In particular, this approach relies on geometrical considerations, providing important properties such as the possibility to multiplex spatially or in wavelength. In addition, it relaxes strongly the constrains on the sensor as no specific plasmon resonances are necessary. We believe this work opens promising alternatives for the development of biosensors.
机译:我们提出了一种新的检测方法,该方法基于要检测的生物分子引起的对称性破坏。简而言之,通过选择呈现出特定对称性(旋转对称性)的传感器,分析物的吸附将破坏这种对称性。通过检测系统对称性的这种变化,可以检测到生物分子的存在。该光学方法提供了优于当前方法的生物传感器概念的实质优势。尤其是,此方法依赖于几何考虑,提供重要的属性,例如在空间或波长上进行复用的可能性。此外,由于不需要特定的等离激元共振,它可以大大放松传感器上的约束。我们相信这项工作为生物传感器的发展开辟了有希望的替代方案。

著录项

  • 来源
  • 会议地点 San Francisco CA(US)
  • 作者单位

    Department of Physics and Astronomy, Macquarie University, 2109 NSW, Australia and ARC Centre of Engineered Quantum System, Macquarie University, 2109 NSW, Australia;

    Department of Physics and Astronomy, Macquarie University, 2109 NSW, Australia and ARC Centre of Engineered Quantum System, Macquarie University, 2109 NSW, Australia;

    Department of Physics and Astronomy, Macquarie University, 2109 NSW, Australia and ARC Centre of Engineered Quantum System, Macquarie University, 2109 NSW, Australia;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    biosensing; symmetry; multiplexing;

    机译:生物传感对称;多路复用;

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