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Integrating Carbon Nanotubes into Microfluidic Chips for Separating Biochemical Compounds

机译:将碳纳米管集成到微流控芯片中以分离生化化合物

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We present a new type of device to separate biochemical compounds wherein carbon nanotubes (CNTs) are integrated as chromatographic stationary phase. The CNTs were directly grown on the bottom of microfluidic channels on Si/SiO_2 substrate by chemical vapor deposition (CVD). Acetylene was used as carbon source and Ni was employed as catalyst. For electrokinetic separations, higher electrical field strength is usually required; therefore, the CNTs were constructed in pillar-array-form by patterning Ni catalyst layer. Electrical field strength of 2.0 kV/cm has been realized, which is more than one order of magnitude higher than the one reported so far. The microfluidic chips integrated with CNTs were successfully used to separate a compound containing two Coumarin dyes, 240 mM C460 and 270 mM C480.
机译:我们提出了一种新型设备,用于分离生化化合物,其中碳纳米管(CNT)被集成为色谱固定相。通过化学气相沉积(CVD)将CNT直接生长在Si / SiO_2衬底上的微流通道底部。乙炔用作碳源,镍用作催化剂。对于电动分离,通常需要更高的电场强度。因此,通过构图Ni催化剂层,以柱状阵列形式构造CNT。已经实现了2.0 kV / cm的电场强度,比迄今为止报道的电场强度高一个数量级。集成有CNT的微流控芯片已成功用于分离包含两种香豆素染料,240 mM C460和270 mM C480的化合物。

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