首页> 外文会议>Nanotechnology amp; applications >CARBON NANOTUBE FIELD-EFFECT TRANSISTOR BIOSENSORS WITH HIGH SIGNAL-TO-NOISE RATIO USING ALTERNATING CURRENT MEASUREMENT
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CARBON NANOTUBE FIELD-EFFECT TRANSISTOR BIOSENSORS WITH HIGH SIGNAL-TO-NOISE RATIO USING ALTERNATING CURRENT MEASUREMENT

机译:使用交替电流测量的碳纳米管场效应晶体管生物传感器,具有高信噪比

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We demonstrated the drastic improvement of sensitivity (signal-to-noise ratio) in carbon nanotube field-effect transistor (CNTFET) sensors. The alternating current (AC) measurement with a lock-in amplifier was adopted to suppress the fluctuations in drain current of CNTFETs without attenuating the signal level. The noise level of CNTFETs incubated in phosphate buffer solution was highly suppressed by the AC measurement. We also investigated the sensing operations of CNTFET pH sensors and biosensors using AC. Sensing performances in CNTFET sensors were dramatically improved. The signal-to-noise ratio of pH sensors measured by AC was six times higher than that by direct current (DC) measurement. Furthermore, a small amount of bovine serum albumin (BSA) of 250 pM was effectively detected by CNTFET biosensors using AC measurement.
机译:我们展示了碳纳米管场效应晶体管(CNTFET)传感器的灵敏度(信噪比)的大幅提高。采用具有锁定放大器的交流电(AC)测量来抑制CNTFET的漏极电流波动,而不会衰减信号电平。通过AC测量可高度抑制在磷酸盐缓冲溶液中孵育的CNTFET的噪声水平。我们还研究了使用AC的CNTFET pH传感器和生物传感器的传感操作。 CNTFET传感器的传感性能得到了显着改善。通过交流电测量的pH传感器的信噪比比通过直流电(DC)测量的信噪比高六倍。此外,CNTFET生物传感器使用交流电测量可有效检测出少量250 pM的牛血清白蛋白(BSA)。

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