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首页> 外文会议>NATO Advanced Study Institute on Polymer Based Systems on Tissue Engineering, Replacement and Regeneration Oct 15-25, 2001 Alvor, Algarve, Portugal >BONE TISSUE ENGINEERING USING STARCH BASED SCAFFOLDS OBTAINED BY DIFFERENT METHODS
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BONE TISSUE ENGINEERING USING STARCH BASED SCAFFOLDS OBTAINED BY DIFFERENT METHODS

机译：使用不同方法获得的基于淀粉的支架进行骨组织工程

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摘要

The materials to be used as scaffolds in tissue engineering must fulfill a number of complex requirements, such as, biocompatibility, appropriate porous structure, mechanical properties and suitable surface chemistry. The selection of the most appropriate polymer to produce the scaffold is a very important step towards the construction of the tissue engineered product since its intrinsic properties will determine in a great extent the properties of the scaffold. However, the method of producing these scaffolds will deeply influence its final characteristics, as it cm dramatically change the type and amount of porosity, the mechanical and degradation behavior, the surface properties and even the biocompatibility of the scaffold mate rial. Several polymers and different processing techniques are beeing studied to produce tissue engineering scaffolds, which, combined with the app opriate type of cells may constitute an effective alternative treatment to mal-functioning organs or tissues, with a dramatic impact on the health and quality of life of patients world-wide. This paper describes our research on tissue engineering using starch based blends and several different and innovative processing methods that are used to produce tissue engineering scaffolds. Preliminary results with osteoblastic cells are also presented.
机译：在组织工程中用作支架的材料必须满足许多复杂的要求，例如生物相容性，合适的多孔结构，机械性能和合适的表面化学。选择最合适的聚合物来生产支架是构建组织工程产品非常重要的一步，因为其内在特性将在很大程度上决定支架的特性。然而，生产这些支架的方法将极大地影响其最终特性，因为它会极大地改变孔隙率的类型和数量，机械和降解行为，表面性能，甚至是生物相容性。正在研究几种聚合物和不同的加工技术来生产组织工程支架，这些支架与适当类型的细胞结合可以构成功能失调的器官或组织的有效替代疗法，对健康和生活质量产生巨大影响世界各地的患者本文介绍了我们对使用淀粉基混合物的组织工程的研究以及用于生产组织工程支架的几种不同的创新加工方法。还显示了成骨细胞的初步结果。

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