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Single shot line-field optical coherence elastography

机译:单发线场光学相干弹性成像

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摘要

Elastic wave imaging optical coherence elastography (EWI-OCE) is an emerging technique that can quantify local biomechanical properties of tissues. However, long acquisition times make this technique unfeasible for clinical use. Here, we demonstrate a noncontact single shot line-field OCE technique using a line-field interferometer and an air-pulse delivery system. The spatial-temporal elastic wave propagation profile was acquired in a single shot and used to quantify the elastic wave group velocity in tissue. Results on tissue-mimicking phantoms and chicken breast muscle agreed well with mechanical compression testing, demonstrating that the presented method can effectively reduce the OCE acquisition time to a few milliseconds in biological application.
机译:弹性波成像光学相干弹性成像(EWI-OCE)是一种新兴技术,可以量化组织的局部生物力学特性。但是,较长的采集时间使该技术在临床上不可行。在这里,我们演示了一种使用线场干涉仪和空气脉冲传输系统的非接触式单发线场OCE技术。一次获取时空弹性波传播剖面,并用于量化组织中的弹性波群速度。组织模拟体模和鸡胸肌的结果与机械压缩测试吻合得很好,证明了该方法在生物应用中可以有效地将OCE采集时间减少到几毫秒。

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  • 来源
  • 会议地点 San Francisco CA(US)
  • 作者单位

    Department of Biomedical Engineering, University of Houston, 3605 Cullen Boulevard, Houston, Texas 77204, USA;

    Department of Biomedical Engineering, University of Houston, 3605 Cullen Boulevard, Houston, Texas 77204, USA;

    Department of Biomedical Engineering, University of Houston, 3605 Cullen Boulevard, Houston, Texas 77204, USA;

    Department of Biomedical Engineering, University of Houston, 3605 Cullen Boulevard, Houston, Texas 77204, USA;

    Department of Biomedical Engineering, University of Houston, 3605 Cullen Boulevard, Houston, Texas 77204, USA;

    Department of Biomedical Engineering, University of Houston, 3605 Cullen Boulevard, Houston, Texas 77204, USA;

    Department of Biomedical Engineering, University of Houston, 3605 Cullen Boulevard, Houston, Texas 77204, USA;

    Department of Biomedical Engineering, University of Houston, 3605 Cullen Boulevard, Houston, Texas 77204, USA;

    Department of Biomedical Engineering, University of Houston, 3605 Cullen Boulevard, Houston, Texas 77204, USA;

    Department of Biomedical Engineering, University of Houston, 3605 Cullen Boulevard, Houston, Texas 77204, USA;

    Department of Biomedical Engineering, University of Houston, 3605 Cullen Boulevard, Houston, Texas 77204, USA,Interdisciplinary Laboratory of Biophotonics, Tomsk State University, Tomsk 634050, Russia,Molecular Physiology and Biophysics, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77584, USA;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Line-field optical coherence tomography; optical coherence elastography; surface wave; cross-correlation; Carre phase shift;

    机译:线场光学相干断层扫描;光学相干弹性成像表面波互相关卡雷相移;

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