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Investigation on laser-assisted tissue repair with NIR millisecond-long light pulses and Indocyanine Green-biopolymeric patches

机译:NIR毫秒级脉冲和吲哚菁绿-生物聚合物贴剂对激光辅助组织修复的研究

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摘要

In previous works a minimally invasive laser-assisted technique for vascular repair was presented. The technique rests on the photothermal adhesion of a biocompatible and bioresorbable patch containing Indocyanine Green that is brought into contact with the site to be repaired. Afterward the use of NIR millisecond-long light pulses generates a strong welding effect between the patch and the underlying tissue and in turn the repair of the wound. This technique was shown to be effective in animal model and provides several advantages over conventional suturing methods. Here we investigate and discuss the optical stability of the ICG-biopolymeric patches and the photothermal effects induced to the irradiated tissue.
机译:在以前的工作中,提出了一种微创激光辅助血管修复技术。该技术基于含有吲哚菁绿的生物相容性和生物可吸收贴剂的光热粘合性,该贴剂与要修复的部位接触。之后,使用NIR毫秒级的光脉冲会在贴片和下面的组织之间产生强烈的焊接效果,进而修复伤口。该技术在动物模型中被证明是有效的,并且比常规缝合方法具有多个优势。在这里,我们研究和讨论了ICG生物聚合物贴片的光学稳定性以及对辐照组织的光热效应。

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