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New sensitizers for PDT

机译：用于PDT的新型敏化剂

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Abstract: For a number of well-defined reasons, research into the development of alternative photosensitizers to Photofrin$+TM$/, for use in Photodynamic Therapy, continues. The efforts described in this paper cover the study of a number of sensitizers absorbing at different wavelengths, which may have selective applications in the field of photomedicine. In one approach, the use of tetraazoporphyrins (porphyrazines) as sensitizers is studied. Although related tetramacrocyclic systems such as porphyrins and phthalocyanines have been, and continue to be, well studied in this field, porphyrazines have, to-date, received little attention. In a second study, purpurins are examined as possible alternatives to Photofrin$+TM$/. In a recent study, tissue distribution properties of tin etiopurpurin dichloride, as a function of time, were examined. Results indicate that this purpurin continues to show promise for applications in PDT.!
机译：摘要：由于许多明确的原因，用于光动力疗法的替代Photofrin $ + TM $ /的光敏剂的研发仍在继续。本文描述的工作涵盖了许多在不同波长吸收的敏化剂的研究，这些敏化剂可能在光医学领域有选择性的应用。在一种方法中，研究了使用四偶氮卟啉（卟啉）作为敏化剂。尽管相关的四大环系统，例如卟啉和酞菁已在该领域得到了很好的研究，并且仍在继续被研究，但迄今为止，卟啉尚未引起人们的关注。在第二项研究中，研究了紫嘌呤作为Photofrin $ + TM $ /的可能替代品。在最近的一项研究中，研究了二氯化紫红紫嘌呤锡的组织分布特性随时间的变化。结果表明，该紫癜继续显示出在PDT中应用的希望。

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