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首页> 外文会议>Optics in health care and biomedical optics VI >Influence of static pressure on dynamic characteristics of laser-induced cavitation and hard-tissue ablation under liquid environment
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Influence of static pressure on dynamic characteristics of laser-induced cavitation and hard-tissue ablation under liquid environment

机译：静态压力对液体环境下激光空化和硬组织消融动力学特性的影响

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摘要

Several studies have demonstrated that laser-induced hard tissue ablation effects can be enhanced by applying an additional water-layer on tissue surface. However, the related mechanism has not yet been presented clearly. In this paper, the influence of static pressure on dynamic characteristics of cavitation induced by pulse laser in liquid and its effect on bovine shank bone ablation were investigated The laser source is fiber-guided free-running Ho:YAG laser with wavelength of 2080 nm, pulse duration of 350 μs and energy of 1600 mJ. The tissue samples were immerged in pure water at different depths of 11, 16, 21, 26 and 31 mm. The working distance between the fiber tip and tissue surface was fixed at 1 mm for all studies. The dynamic interaction between laser, water and tissue were recorded by high-speed camera, and the morphological changes of bone tissue were assessed by stereomicroscope and OCT. The results showed that many times expansion and collapse of bubble were observed, more than four pulsation periods were accurately achieved with the most energy deposited in the first period and the bubble became more and more irregular in shape. The longitudinal length (7.49-6.74 mm) and transverse width (6.69-6.08 mm) of bubble were slowly decreased while volume (0.0586-0.0124 mm~3) of ablation craters were drastically reduced, with static pressure increasing. The results also presented that the water-layer on hard-tissue surface can not only reduce thermal injury but also improve lubricity of craters, although the water-layer reduced ablation efficiency.
机译：多项研究表明，通过在组织表面施加额外的水层，可以增强激光诱导的硬组织消融作用。但是，相关机制尚未明确提出。本文研究了静压对脉冲激光在液体中引起的空化动力学特性的影响及其对牛小腿骨消融的影响。激光源为光纤制导的自由运行的Ho：YAG激光，波长为2080 nm，脉冲持续时间为350μs，能量为1600 mJ。将组织样品浸入纯水中，浸入深度分别为11、16、21、26和31 mm。对于所有研究，纤维尖端与组织表面之间的工作距离固定为1 mm。用高速相机记录激光，水和组织之间的动态相互作用，并用立体显微镜和OCT评估骨组织的形态变化。结果表明，多次观察到气泡的膨胀和破裂，在第一阶段沉积的能量最多的情况下，准确地实现了四个以上的脉动周期，并且气泡的形状变得越来越不规则。气泡的纵向长度（7.49-6.74 mm）和横向宽度（6.69-6.08 mm）逐渐减小，而烧蚀弹坑的体积（0.0586-0.0124 mm〜3）则显着减小，而静压则增大。结果还表明，尽管水层降低了烧蚀效率，但硬组织表面的水层不仅可以减少热损伤，而且还可以改善弹坑的润滑性。

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  • 来源
    《Optics in health care and biomedical optics VI》|2014年|92682C.1-92682C.8|共8页
  • 会议地点 Beijing(CN)
  • 作者

    Chuanguo Chen; Xuwei Li; Xianzeng Zhang; Zhenlin Zhan; Shusen Xie;

  • 作者单位

    Institute of Laser and Optoelectronics Technology, Fujian Provincial Key Laboratory for Photonics Technology, Key Laboratory of Optoelectronic Science and Technology for Medicine of Ministry of Education, Fujian Normal University, Fuzhou, Fujian 350007, China;

    Institute of Laser and Optoelectronics Technology, Fujian Provincial Key Laboratory for Photonics Technology, Key Laboratory of Optoelectronic Science and Technology for Medicine of Ministry of Education, Fujian Normal University, Fuzhou, Fujian 350007, China;

    Institute of Laser and Optoelectronics Technology, Fujian Provincial Key Laboratory for Photonics Technology, Key Laboratory of Optoelectronic Science and Technology for Medicine of Ministry of Education, Fujian Normal University, Fuzhou, Fujian 350007, China;

    Institute of Laser and Optoelectronics Technology, Fujian Provincial Key Laboratory for Photonics Technology, Key Laboratory of Optoelectronic Science and Technology for Medicine of Ministry of Education, Fujian Normal University, Fuzhou, Fujian 350007, China;

    Institute of Laser and Optoelectronics Technology, Fujian Provincial Key Laboratory for Photonics Technology, Key Laboratory of Optoelectronic Science and Technology for Medicine of Ministry of Education, Fujian Normal University, Fuzhou, Fujian 350007, China;

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  • 正文语种 eng
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  • 关键词

    water-layer; hard-tissue ablation; cavitation bubble; Ho: YAG laser; high-speed camera; craters;

    机译：水层硬组织消融；空化气泡何：YAG激光；高速相机；火山口;

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