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首页> 外文会议>Opto-Acoustic Methods and Applications in Biophotonics II >Coregistered Photoacoustic and ultrasound tomography of healthy and inflamed human interphalangeal joints
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Coregistered Photoacoustic and ultrasound tomography of healthy and inflamed human interphalangeal joints

机译：健康和发炎的人指间关节的共注册光声和超声断层扫描

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摘要

Photoacoustic (PA) or optoacoustic (OA) imaging combines the high (blood) contrast to light with the high-resolution of ultrasound. The method can visualize vascularization deep inside tissue. Of late there is interest in PA imaging of synovial joints which are expected to be associated with increased vascularization in the event of rheumatoid arthritis (RA). We here describe our approach in investigating the application of the PA technique in arthritis. We are developing a CT-geometry version PA finger imager, intended for early clinical assessment of the method. The imager uses two curved array ultrasound detectors each with 64 elements with central frequencies 1.5 and 7.5 MHz respectively, stacked above each other. Both cover approximately 180 degrees of the circle. Illumination is provided with a multiple of optical fiber bundles coupled to a laser-OPO system. Ultrasound imaging is also possible with the system, since the curved arrays are each provided with 12 or 8 ultrasound pulsers. We have investigated systematically imaging of finger vasculature in healthy volunteers using an earlier laboratory prototype. In this paper we present finger imaging results of a patient diagnosed with rheumatoid arthritis.
机译：光声（PA）或光声（OA）成像结合了光的高（血液）对比度和高分辨率的超声。该方法可以可视化组织内部深处的血管形成。最近，人们对滑膜关节的PA成像感兴趣，在风湿性关节炎（RA）的情况下，滑膜关节的PA成像有望与增加的血管形成有关。在这里，我们描述了研究PA技术在关节炎中的应用的方法。我们正在开发CT几何版本的PA手指成像仪，旨在对该方法进行早期临床评估。该成像仪使用两个曲面阵列超声波检测器，每个检测器具有64个元件，每个元件的中心频率分别为1.5和7.5 MHz，彼此叠置。两者都覆盖圆的大约180度。照明是由多个与激光-OPO系统耦合的光纤束提供的。该系统还可以进行超声成像，因为每个曲面阵列都配备有12个或8个超声脉冲发生器。我们已经使用较早的实验室原型系统地研究了健康志愿者中手指脉管系统的成像。在本文中，我们介绍了诊断为类风湿关节炎的患者的手指成像结果。

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  • 来源
  • 会议地点 Munich(DE)
  • 作者

    Peter van Es; Redmar C. Vlieg; Erwin Hondebrink; Johan C. G. van Hespen; Hein J. Bernelot Moens; Wiendelt Steenbergen; Srirang Manohar;

  • 作者单位

    Biomedical Photonic Imaging Group, MIRA-Institute for Biomedical Technology and Technical Medicine, University of Twente, P.O. Box 217, 7500 AE Enschede, The Netherlands;

    Biomedical Photonic Imaging Group, MIRA-Institute for Biomedical Technology and Technical Medicine, University of Twente, P.O. Box 217, 7500 AE Enschede, The Netherlands;

    Biomedical Photonic Imaging Group, MIRA-Institute for Biomedical Technology and Technical Medicine, University of Twente, P.O. Box 217, 7500 AE Enschede, The Netherlands;

    Biomedical Photonic Imaging Group, MIRA-Institute for Biomedical Technology and Technical Medicine, University of Twente, P.O. Box 217, 7500 AE Enschede, The Netherlands;

    Ziekenhuis Groep Twente, Department of Rheumatology, Postbus 546, 7550 AM Hengelo, The Netherlands;

    Biomedical Photonic Imaging Group, MIRA-Institute for Biomedical Technology and Technical Medicine, University of Twente, P.O. Box 217, 7500 AE Enschede, The Netherlands;

    Biomedical Photonic Imaging Group, MIRA-Institute for Biomedical Technology and Technical Medicine, University of Twente, P.O. Box 217, 7500 AE Enschede, The Netherlands;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    photoacoustic imaging; optoacoustic imaging; ultrasound tomography; rheumatoid arthritis; finger joint imaging; imaging of inflamed synovium;

    机译：光声成像光声成像超声层析成像类风湿关节炎;手指关节成像；滑膜发炎的影像学;

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