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Advantages of semiconductor CZT for medical imaging

机译:半导体CZT在医学成像中的优势

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摘要

Cadmium zinc telluride (CdZnTe, or CZT) is a room-temperature semiconductor radiation detector that has been developed in recent years for a variety of applications. CZT has been investigated for many potential uses in medical imaging, especially in the field of single photon emission computed tomography (SPECT). CZT can also be used in positron emission tomography (PET) as well as photon-counting and integration-mode x-ray radiography and computed tomography (CT). The principal advantages of CZT are 1) direct conversion of x-ray or gamma-ray energy into electron-hole pairs; 2) energy resolution; 3) high spatial resolution and hence high space-bandwidth product; 4) room temperature operation, stable performance, high density, and small volume; 5) depth-of-interaction (DOI) available through signal processing. These advantages will be described in detail with examples from our own CZT systems. The ability to operate at room temperature, combined with DOI and very small pixels, make the use of multiple, stationary CZT 'mini-gamma cameras" a realistic alternative to today's large Anger-type cameras that require motion to obtain tomographic sampling. The compatibility of CZT with Magnetic Resonance Imaging (MRI)-fields is demonstrated for a new type of multi-modality medical imaging, namely SPECT/MRI. For pre-clinical (I.e., laboratory animal) imaging, the advantages of CZT lie in spatial and energy resolution, small volume, automated quality control, and the potential for DOI for parallax removal in pinhole imaging. For clinical imaging, the imaging of radiographically dense breasts with CZT enables scatter rejection and hence improved contrast. Examples of clinical breast images with a dual-head CZT system are shown.
机译:碲化镉锌(CdZnTe或CZT)是一种室温半导体辐射探测器,近年来已开发用于多种应用。已对CZT在医学成像中的许多潜在用途进行了研究,尤其是在单光子发射计算机断层扫描(SPECT)领域。 CZT还可以用于正电子发射断层扫描(PET)以及光子计数和积分模式X射线射线照相以及计算机断层扫描(CT)。 CZT的主要优点是:1)将X射线或γ射线能量直接转换为电子-空穴对; 2)能量分辨率; 3)高空间分辨率,从而产生高空间带宽积; 4)常温运行,性能稳定,密度高,体积小; 5)可以通过信号处理获得交互深度(DOI)。这些优势将通过我们自己的CZT系统中的示例进行详细描述。能够在室温下运行,结合DOI和很小的像素,使得使用多个固定的CZT“微型伽马相机”成为当今大型Anger型相机的现实选择,后者需要运动来获取断层图像采样。磁共振成像(MRI)领域的CZT成像技术被证明用于新型的多模态医学成像,即SPECT / MRI。对于临床前(即实验室动物)成像,CZT的优势在于空间和能量分辨率,小体积,自动质量控制以及针孔成像中消除视差的DOI潜力。对于临床成像,使用CZT对放射线密集的乳房进行成像可消除散射并因此改善对比度。显示了头CZT系统。

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