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首页> 外文会议>Photons Plus Ultrasound: Imaging and Sensing 2006; Progress in Biomedical Optics and Imaging; vol.7, no.9 >Ultrasonically Modulated X-Ray Phase Contrast and Vibration Potential Imaging Methods
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Ultrasonically Modulated X-Ray Phase Contrast and Vibration Potential Imaging Methods

机译：超声调制的X射线相衬和振动电位成像方法

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摘要

We show that the radiation pressure exerted by a beam of ultrasound can be used for contrast enhancement in high resolution x-ray imaging of tissue. Interfacial features of objects are highlighted as a result of both the displacement introduced by the ultrasound and the inherent sensitivity of x-ray phase contrast imaging to density variations. The potential of the method is demonstrated by imaging various tumor phantoms and tumors from mice. The directionality of the acoustic radiation force and its localization in space permits the imaging of ultrasound-selected tissue volumes. In a related effort we report progress on development of an imaging technique using and electrokinetic effect known as the ultrasonic vibration potential. The ultrasonic vibration potential refers to the voltage generated when ultrasound traverses a colloidal or ionic fluid. The theory of imaging based on the vibration potential is reviewed, and an expression given that describes the signal from an arbitrary object. The experimental apparatus consists of a pair of parallel plates connected to the irradiated body, a low noise preamplifier, a radio frequency lock-in amplifier, translation stages for the ultrasonic transducer that generates the ultrasound, and a computer for data storage and image formation. Experiments are reported where bursts of ultrasound are directed onto colloidal silica objects placed within inert bodies.
机译：我们表明，由超声波束施加的辐射压力可用于组织的高分辨率X射线成像中的对比度增强。由于超声波引入的位移以及X射线相衬成像对密度变化的固有敏感性，结果突出了对象的界面特征。通过对各种肿瘤体模和小鼠肿瘤成像，证明了该方法的潜力。声辐射力的方向性及其在空间中的位置允许对超声选择的组织体积进行成像。在相关的工作中，我们报告了使用超声振动势和电动势的成像技术发展的进展。超声振动势是指当超声穿过胶体或离子流体时产生的电压。回顾了基于振动势能的成像原理，并给出了描述来自任意物体的信号的表达式。实验装置由一对与辐射体相连的平行板，一个低噪声前置放大器，一个射频锁定放大器，用于产生超声的超声换能器的平移台以及用于数据存储和图像形成的计算机组成。据报道，有实验将超声波脉冲对准放置在惰性体内的胶体二氧化硅物体。

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