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首页> 外文会议>Physiology, Function, and Structure from Medical Images pt.2; Progress in Biomedical Optics and Imaging; vol.7,no.29 >Multislice CT perfusion imaging of the lung in detection of pulmonary embolism
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Multislice CT perfusion imaging of the lung in detection of pulmonary embolism

机译：肺部多层CT灌注成像在检测肺栓塞中的作用

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摘要

We propose a new subtraction technique for accurately imaging lung perfusion and efficiently detecting pulmonary embolism in chest MDCT angiography. Our method is composed of five stages. First, optimal segmentation technique is performed for extracting same volume of the lungs, major airway and vascular structures from pre- and post-contrast images with different lung density. Second, initial registration based on apex, hilar point and center of inertia (COI) of each unilateral lung is proposed to correct the gross translational mismatch. Third, initial alignment is refined by iterative surface registration. For fast and robust convergence of the distance measure to the optimal value, a 3D distance map is generated by the narrow-band distance propagation. Fourth, 3D nonlinear filter is applied to the lung parenchyma to compensate for residual spiral artifacts and artifacts caused by heart motion. Fifth, enhanced vessels are visualized by subtracting registered pre-contrast images from post-contrast images. To facilitate visualization of parenchyma enhancement, color-coded mapping and image fusion is used. Our method has been successfully applied to ten patients of pre- and post-contrast images in chest MDCT angiography. Experimental results show that the performance of our method is very promising compared with conventional methods with the aspects of its visual inspection, accuracy and processing time.
机译：我们提出了一种新的减影技术，用于精确地成像肺灌注并有效地检测胸部MDCT血管造影术中的肺栓塞。我们的方法包括五个阶段。首先，执行最佳分割技术以从具有不同肺密度的造影前后图像中提取相同体积的肺，主要气道和血管结构。其次，提出基于每个单侧肺的顶点，肺门点和惯性中心（COI）的初始配准，以纠正总体翻译不匹配。第三，通过对齐的曲面配准来优化初始对齐。为了将距离度量快速而稳健地收敛到最佳值，可通过窄带距离传播生成3D距离图。第四，将3D非线性滤波器应用于肺实质，以补偿残留的螺旋伪影和由心脏运动引起的伪影。第五，通过从对比后图像减去配准的对比前图像来可视化增强的血管。为了促进实质增强的可视化，使用了颜色编码的映射和图像融合。我们的方法已成功应用于胸部MDCT血管造影术中的10例造影前后的患者。实验结果表明，与常规方法相比，我们的方法在外观，准确性和处理时间方面都具有很大的发展前景。

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