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首页> 外文会议>Proceedings of the 18th congress of the International Society for Mushroom Science >The Comparative Study of Lentinus edodes Caps and Stems Influence on Injuries of Gastric Mucosa in Rats Evoked by Stress
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The Comparative Study of Lentinus edodes Caps and Stems Influence on Injuries of Gastric Mucosa in Rats Evoked by Stress

机译：香菇帽和茎对应激所致大鼠胃粘膜损伤影响的比较研究

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Earlier, we have shown that treatment with dry fruiting body of Lentinus edodes (Berg.) Singer inhibited injuries formation in stressed rats. But, stems of shiitake are rarely used, primarily because the stems are harder and take longer to cook than the soft fleshy caps and as a result lost a mushroom material that could have therapeutic properties. Therefore the aim of this study was to compare the protection effect of caps and stems of Lentinus edodes in model of stress-induced gastric ulcerogenesis in rats. Rats were randomly assigned to one of five groups, all group were exposed to stress. Each group consisted of seven animals. Jelly starch (control group) and jelly starch powder suspensions of caps and stems from two strains Lentinus edodes (200 mg/kg, i. g.), were administered in 0. 5mL volumes, daily, during a 7-day period. The animals were stressed on fifth day, and they were sacrificed on eighth days after starting experiment. Animals were exposed to acute immobilization stress combined with water immersion for 180 minutes. Restrained in metal perforated containers rats were immersed in the water bath (22℃) in such a way that the head of the animal was outside of water. Gastric wounds were classified as erosions and ulcers. The treatment with caps of Lentinus edodes inhibited ulcers formation by 75% and 80% respectively for strain 1 and 2, compared to the control group (P<0. 05) and erosion formation by 58. 8% for strain 1. Administration of stems of Lentinus edodes inhibited ulcers formation by 70% and inhibit erosion formation by 60. 7% (P<0. 05) for strain 1. For other groups presented only unproven activity. Therefore, we concluded that it is possible to use Lentinus edodes stems by gastric ulcer disease patients as a health food may help in the clinical situation as a prophylactic agent, and in healthy persons as stress-protective agents.
机译：之前，我们已经证明，用香菇干子实体（Berg。）Singer进行治疗可抑制压力大鼠的损伤形成。但是，香菇的茎很少使用，主要是因为茎比柔软的肉质帽更硬，煮制所需的时间更长，结果失去了可能具有治疗特性的蘑菇材料。因此，本研究的目的是比较香菇帽和茎在大鼠应激性胃溃疡发生模型中的保护作用。将大鼠随机分为五组之一，所有组均承受压力。每组由七只动物组成。在7天的期间内，每天以0. 5mL的体积施用果冻淀粉（对照组）和来自两个菌株香菇（200 mg / kg，即g。）的盖和茎的果冻淀粉粉末悬浮液。在第五天给动物施加压力，并在开始实验后第八天将它们处死。使动物暴露于急性固定压力并结合水浸泡180分钟。将老鼠约束在金属穿孔的容器中，将其浸泡在22℃的水浴中，以使动物的头部不在水中。胃伤口被分类为糜烂和溃疡。与对照组（P <0。05）相比，香菇加盖处理对菌株1和2的溃疡形成分别抑制了75％和80％，对菌株1则抑制了58. 8％的糜烂形成。对于菌株1，香菇的抑制作用抑制了70％的溃疡形成，抑制了60.7％的糜烂形成（P <0。05）。其他组仅表现出未经证实的活性。因此，我们得出结论，可以将胃溃疡病患者使用的香菇茎作为保健食品，在临床上可以作为预防剂，而在健康人中用作压力保护剂。

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