Simulation of cervical cancer response to radiotherapy

机译：宫颈癌对放射治疗反应的模拟

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The goal of this article is to present basic scientific principles and core algorithms of the simulation module of the CERvical cancer ONCOsimulator (CERONCO) developed within the context of the DrTherapat project (FP7-ICT-600852). CERONCO simulates the response of cervical tumours to radiotherapy treatment (external beam radiotherapy followed by brachytherapy) with concomitant weekly cisplatin, in the patient-individualized context. Results from a preliminary clinical adaptation study based on the MR imaging data of a clinical case are presented as well.

机译：本文的目的是介绍在DrTherapat项目（FP7-ICT-600852）的背景下开发的宫颈癌ONCOsimulator（CERONCO）模拟模块的基本科学原理和核心算法。 CERONCO在患者个体化的情况下，模拟伴随每周一次顺铂进行放疗（子宫颈放疗后近距离放疗）对宫颈肿瘤的反应。还介绍了基于临床病例的MR图像数据进行的初步临床适应性研究的结果。

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来源
《Proceedings of the 2014 6th International Advanced Research Workshop on In Silico Oncology and Cancer Investigation - The TUMOR Project Workshop》|2014年|1-4|共4页
会议地点 Athens(GR)
作者
Kyroudis Christos /A/.; Dionysiou Dimitra D.; Kolokotroni Eleni /A/.; Kallehague Jesper F.; Tanderup Kari; Stamatakos Georgios S.;
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作者单位

In Silico Oncology Group, Nat. Tech. Univ. of Athens, Athens, Greece;

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原文格式 PDF
正文语种 eng
中图分类
关键词
biomedical MRI; brachytherapy; cancer; tumours; CERONCO; CERvical cancer ONCOsimulator; MR imaging data; brachytherapy; cervical cancer simulation; cervical tumour; external beam radiotherapy; radiotherapy treatment; Biological system modeling; Tumors;

机译：生物医学MRI;近距离放射治疗;癌症;肿瘤; CERONCO;宫颈癌ONCOsimulator; MR成像数据;近距离放射治疗;子宫颈癌模拟;宫颈肿瘤;外放射线放射疗法;放射治疗;生物系统建模;肿瘤;;

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1. Completion surgery after chemoradiotherapy for cervical cancer - is there a role? UK Cancer Centre experience of hysterectomy post chemo-radiotherapy treatment for cervical cancer [J] . Platt Sarah L., Patel Amit, Humphrey Pauline J., Journal of obstetrics and gynaecology: the journal of the Institute of Obstetrics and Gynaecology . 2019,第1期

机译：宫颈癌切换后的完成手术 - 是否存在作用？英国癌症中心经验经历宫颈癌术后化疗治疗宫颈癌
2. Effects of preoperative radiotherapy or chemoradiotherapy on postoperative pathological outcome of cervical cancer-from the large database of 46,313 cases of cervical cancer in China [J] . Li Weili, Liu Ping, Zhao Weidong, European Journal of Surgical Oncology: The Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology . 2020,第1期

机译：术前放疗或化疗疗法对宫颈癌术后病理结果的影响 - 来自中国46,313例宫颈癌的大型数据库
3. Dosimetric study of volumetric arc modulation with RapidArc and intensity-modulated radiotherapy in patients with cervical cancer and comparison with 3-dimensional conformal technique for definitive radiotherapy in patients with cervical cancer [J] . Guy Jean-Baptiste, Falk Alexander T., Auberdiac Pierre, Medical dosimetry: official journal of the American Association of Medical Dosimetrists . 2016,第1期

机译：宫颈癌患者使用RapidArc和强度调制放疗进行容积弧调制的剂量学研究，以及与3D保形技术进行宫颈癌最终放疗的比较
4. Simulation of cervical cancer response to radiotherapy [C] . Kyroudis Christos /A/., Dionysiou Dimitra D., Kolokotroni Eleni /A/., International Advanced Research Workshop on In Silico Oncology and Cancer Investigation . 2014

机译：宫颈癌反应对放射疗法的模拟
5. A case for multiple item response theory: The Cancer Health Literacy Measure-Breast and Cervical Cancer-Uruguay. [D] . Linares, Deborah E. 2015

机译：多项目反应理论的一个案例：《癌症健康素养测度-乳腺癌和宫颈癌-乌拉圭》。
6. Evaluation of pelvic lymph node coverage of conventional radiotherapy fields based on bony landmarks in Chinese cervical cancer patients using CT simulation [O] . Xiang Zhang, Hua Yu 2009

机译：利用CT模拟评估骨癌标志物对传统放射治疗领域骨盆淋巴结的覆盖率
7. Apparent diffusion coefficient histogram shape analysis for monitoring early response in patients with advanced cervical cancers undergoing concurrent chemo-radiotherapy [O] . 2016

机译：表观扩散系数直方图形状分析用于监测接受同步放疗的晚期宫颈癌患者的早期反应

Simulation of cervical cancer response to radiotherapy

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