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首页> 外文会议>Proceedings of the 3rd Pan American materials congress >Injectability Evaluation of Bone-Graft Substitutes Based on Carrageenan and Hydroxyapatite Nanorods
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Injectability Evaluation of Bone-Graft Substitutes Based on Carrageenan and Hydroxyapatite Nanorods

机译：基于角叉菜胶和羟基磷灰石纳米棒的骨接枝替代品的可注射性评估

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摘要

The first injectable bone substitutes were introduced for orthopedic trauma applications since more than a decade, and over recent years the number of commercial products has dramatically increased. These substitutes can be injected into a fracture space for augmentation as an alternative to bone graft, or around a screw for augmentation if the bone is weak, so the injectability of the substitute must be optimum with a good behavior within and our of syringe. The aim of this work was to study the injectability of substitutes based on carrageenan CG with 1, 1.5, 2.5 and 60 wt% hydroxyapatite HA nanorods. Initially carrageenan and hydroxyapatite were characterized and then injectability tests were performed with the syringe between the compression plates of a testing machine. The material also was characterized by scanning electron microscopy. The results revealed that none of the samples had phases separation and they did not exceed 300 N of force (97.08, 107.84 and 149 N to each material), that the injectability was 95.71, 93.69 and 90.63% and the CG was a good vehicle for HA nanorods. Therefore, the substitutes are adequate for manual handling.
机译：十多年来，第一款可注射的骨替代物被引入骨科创伤治疗领域，近年来，商业产品的数量急剧增加。可以将这些替代物注射到骨折腔中以作为骨移植的替代物进行填充，或者如果骨骼较弱，则可以在螺钉周围进行填充，因此，替代物的可注射性必须是最佳的，并且必须在注射器内和注射器内均具有良好的性能。这项工作的目的是研究基于角叉菜胶CG的替代品的可注射性，其中包含1,5％，2.5％和60％（重量）的羟基磷灰石HA纳米棒。最初对角叉菜胶和羟基磷灰石进行了表征，然后使用注射器在测试机压缩板之间进行了可注射性测试。该材料还通过扫描电子显微镜表征。结果显示，所有样品均没有相分离，并且没有超过300 N的力（每种材料的力分别为97.08、107.84和149 N），可注射性分别为95.71％，93.69％和90.63％，并且CG对于HA纳米棒。因此，这些替代品足以进行人工处理。

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