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Optimization of the Fermentation Process for Streptomyces lydicus A02 Producing Natamycin

机译:产纳他霉素的链霉菌A02发酵工艺的优化

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摘要

@@ Streptomyces lydicus A02 was isolated from forest soil in a suburb of Beijing. The strain presented a stable and strong antagonistic activity against many plant pathogenic fungi, such as Botrytis cinerea,Alternaria solani, Fusarium graminearum,Rhizoctonia cerealis and others. Studies showed that the main active component of strain A02 is natamycin, a natural fungicides. We have developed a microcapsule formulation of natamycin produced by strain A02. Using the microencapsulated natamycin, high control efficiencies towards vegetable grey molds (up to appr. 90%) were obtained by potted plant trials performed in the greenhouse. In order to increasing productivity and reducing production costs of the natural fungicides, we optimized the fed batch fermentation process of Streptomyces lydicus A02 producing natamycin.
机译:LY。链霉菌A02是从北京郊区的森林土壤中分离出来的。该菌株对许多植物病原真菌,如灰葡萄孢,褐藻,禾谷镰刀菌,谷物根瘤菌等,均表现出稳定而强烈的拮抗活性。研究表明,菌株A02的主要活性成分是那他霉素,一种天然的杀菌剂。我们已经开发了由菌株A02产生的那他霉素的微胶囊制剂。使用微囊化纳他霉素,通过在温室中进行盆栽试验,获得了对蔬菜灰霉病的高防治效率(最高约90%)。为了提高天然杀真菌剂的生产率并降低生产成本,我们优化了产纳他霉素的链霉菌A02的补料分批发酵工艺。

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