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首页> 外文会议>Proceedings of Life in space for life on earth >DIFFERENTIAL RESPONSES OF SOLEUS AND PLANTARIS MUSCLE FIBERS TO OVERLOADING
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DIFFERENTIAL RESPONSES OF SOLEUS AND PLANTARIS MUSCLE FIBERS TO OVERLOADING

机译：柑桔和车前子肌纤维对超负荷的不同反应

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摘要

Responses of slow and fast fibers in soleus andrnplantaris muscles of adult rats to overloading by therntendon transection of synergists were studied.rnOverloading-related hypertrophy was noted in the slowrnfibers of plantaris and soleus, although the magnitudernwas greater in plantaris. Five genes with minorrnexpression in slow soleus muscle were identified byrnmicroarray analysis. Base-line expressions of theserngenes in slow fibers of plantaris were also low. Further,rnrepressive effects of overloading on these genes werernseen in some fast fibers of plantaris, not in wholernplantaris and soleus. The data suggested that thernrepression of particular genes might be related to thernpronounced morphological response of fibers expressingrntype II, including I+II, myosin heavy chain (MyHC),rnalthough these genes with lower base-line expression inrnslow fibers did not respond to overloading.
机译：研究了成年大鼠比目鱼肌和比目鱼肌慢速和快速纤维对增效剂的超负荷反应。在ari肌和比目鱼肌的慢纤维中发现了与超负荷有关的肥大，尽管plant肌的幅度更大。通过微阵列分析鉴定了比目鱼肌缓慢表达的五个基因。 s属慢纤维中的serngenes的基线表达也很低。此外，在一些fast鱼的快速纤维中，而不是在整个plant鱼和比目鱼肌中，可见超载对这些基因的抑制作用。数据表明，特定基因的抑制可能与表达II型纤维（包括I + II，肌球蛋白重链（MyHC））的发音的形态反应有关，尽管这些具有较低基线表达的基因对慢纤维没有反应。

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  • 会议地点 Aberdeen(GB)
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    Fuminori Kawano; Tsubasa Shibaguchi; Takashi Ohira; Naoya Nakai; Yoshinobu Ohira;

  • 作者单位

    Graduate School of Medicine , Osaka University, Toyonaka City, 560-0043, Osaka, Japan el: +81-6-6850-6018 Fax: +81-6-6850-6030 E-mail: kawaco@space.hss.osaka-u.ac.jp;

    Graduate School of Frontier Biosciences, Osaka University, Toyonaka City, 560-0043, Osaka, Japan;

    Graduate School of Frontier Biosciences, Osaka University, Toyonaka City, 560-0043, Osaka, Japan;

    Graduate School of Medicine , Osaka University, Toyonaka City, 560-0043, Osaka, Japan;

    Graduate School of Medicine , Osaka University, Toyonaka City, 560-0043, Osaka, Japan Graduate School of Frontier Biosciences, Osaka University, Toyonaka City, 560-0043, Osaka, Japan;

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