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首页> 外文会议>Proceedings of Life in space for life on earth >EFFECTS OF HDT BED REST ON EXCITABILITY OF THE SARCOLEMMA IN POSTURAL MUSCLES
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EFFECTS OF HDT BED REST ON EXCITABILITY OF THE SARCOLEMMA IN POSTURAL MUSCLES

机译：HDT床休息对姿势性肌肉中脊膜兴奋性的影响

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摘要

Prolonged decrease in physical activity level during bedrnrest leads to a decrease in muscle mass and force. Arndecrease in protein synthesis should be one of the mainrncauses for the muscle atrophy and weakness.rnAdditionally, a decrease in the sarcolemmal excitabilityrnmay also contribute to the muscle weakness. After 21-rnday head tilt down (HDT) bed rest (BR) we have foundrnthat markedly decreased force in knee extensors andrnplantar flexors was accompanied by significantrnprolongation of the compound muscle action potentialrn(m-wave) in m. vastus lateralis (VL) (+3.5%) and in m.rngastrocnemius medialis (GM) (+8.1%). In this study, wernstudied effects of the 5-days HDT BR in the samernmuscles. 10 subjects were tested before, after, and 5rndays after the bed rest. In contrast to the 21-days BR,rnthe 5-days BR did not lead to changes in m-wavesrnparameters. These findings show that effects of thernHDT bed rest on the sarcolemmal excitability depend onrnits duration and are not directly associated with the fluidrnshift in lower extremities.
机译：卧床休息期间身体活动水平的持续下降会导致肌肉质量和力量下降。蛋白质合成中的Arnase减少应该是造成肌肉萎缩和无力的主要原因之一。此外，肌膜兴奋性的降低也可能导致肌肉无力。经过21天的头部俯卧（HDT）卧床休息（BR），我们发现膝关节伸肌和足底屈肌力显着降低，同时复合肌动作电位（m波）显着延长。股外侧肌（VL）（+ 3.5％）和内侧腓肠肌（GM）（+ 8.1％）。在这项研究中，我们研究了5天HDT BR在同一肌肉中的作用。在卧床休息之前，之后和5天后对10位受试者进行了测试。与21天的BR相比，5天的BR没有导致m波参数的变化。这些发现表明，HDT卧床休息对肌膜兴奋性的影响取决于持续时间，并且与下肢的流体移位没有直接关系。

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  • 会议地点 Aberdeen(GB)
  • 作者

    Shushakov V.; Grunewald M.; Maassen N.; Zange J.;

  • 作者单位

    Hannover Medical School, Carl-Neuberg-Str.1, D-30625 Hanover Germany, Email: chouchakov.vladimir@mh-hannover.de;

    Hannover Medical School, Carl-Neuberg-Str.1, D-30625 Hanover Germany;

    Hannover Medical School, Carl-Neuberg-Str.1, D-30625 Hanover Germany,University of Hannover, Institute of Sport Science, Am Moritzwinkel 6 30167 Hanover Germany, Email: Maassen.Norbert@mh-hannover.de;

    DLR, German Aerospace Center, Institute of Aerospace Medicine, Linder H?he 51147 K?ln Germany,Email: Jochen.Zange@dlr.de;

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