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首页> 外文会议>Quantitative phase imaging III >Optical Projection Tomography via Phase Retrieval Algorithms for Hidden Three Dimensional Imaging
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Optical Projection Tomography via Phase Retrieval Algorithms for Hidden Three Dimensional Imaging

机译：通过相位检索算法进行光学投影层析成像，以进行隐藏的三维成像

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摘要

Optical tomography in biomedical imaging is a highly dynamic field in which non-invasive optical and computational techniques are combined to obtain a three dimensional representation of the specimen we are interested to image. Although at optical wavelengths scattering is the main obstacle to reach diffraction limited resolution, recently several studies have shown the possibility to image even objects fully hidden behind a turbid layer exploiting the information contained in the speckle autocorrelation via an iterative phase retrieval algorithm. In this work we explore the possibility of blind three dimensional reconstruction approach based on the Optical Projection Tomography principles, a widely used tool to image almost transparent model organism such as C. Elegans and D. Rerio. By using autocorrelation information rather than projections at each angle we prove, both numerically and experimentally, the possibility to perform exact three dimensional reconstructions via a specifically designed phase retrieval algorithm, extending the capability of the projection-based tomographic methods to image behind scattering curtains. The reconstruction scheme we propose is simple to implement, does not require post-processing data alignment and moreover can be trivially implemented in parallel to fully exploit the computing power offered by modern GPUs, further reducing the need for costly computational resources.
机译：生物医学成像中的光学层析成像是一个高度动态的领域，在该领域中，非侵入性光学和计算技术相结合以获得我们感兴趣成像的标本的三维表示。尽管在光波长处散射是达到衍射极限分辨率的主要障碍，但最近的一些研究表明，利用散斑自相关中包含的信息，通过迭代相位检索算法，甚至可以将完全隐藏在浑浊层后面的物体成像。在这项工作中，我们探索了基于光学投影层析成像原理的盲三维重建方法的可能性，光学投影层析成像原理是一种用于对几乎透明的模型生物（例如C. Elegans和D. Rerio）进行成像的工具。通过使用自相关信息而不是每个角度的投影，我们在数值上和实验上都证明了通过专门设计的相位检索算法执行精确的三维重建的可能性，从而将基于投影的层析成像方法的功能扩展到了散射幕后的图像。我们提出的重构方案易于实现，不需要后处理数据对齐，而且可以并行实现琐碎的操作，以充分利用现代GPU提供的计算能力，从而进一步减少了对昂贵的计算资源的需求。

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  • 来源
    《Quantitative phase imaging III》|2017年|100741E.1-100741E.7|共7页
  • 会议地点 San Francisco(US)
  • 作者

    Daniele Ancora; Diego Di Battista; Georgia Giasafaki; Stylianos Psycharakis; Evangelos Liapis; Athanasios Zacharopoulos; Giannis Zacharakis;

  • 作者单位

    Institute of Electronic Structure and Laser - Foundation for Research and Technology Hellas, (FORTH-IESL) Heraklion, Greece,Department of Material Science - University of Crete, Heraklion, Greece;

    Institute of Electronic Structure and Laser - Foundation for Research and Technology Hellas, (FORTH-IESL) Heraklion, Greece,Department of Material Science - University of Crete, Heraklion, Greece;

    Department of Medicine - University of Crete, Heraklion, Greece;

    Institute of Electronic Structure and Laser - Foundation for Research and Technology Hellas, (FORTH-IESL) Heraklion, Greece;

    Institute of Electronic Structure and Laser - Foundation for Research and Technology Hellas, (FORTH-IESL) Heraklion, Greece;

    Institute of Electronic Structure and Laser - Foundation for Research and Technology Hellas, (FORTH-IESL) Heraklion, Greece;

    Institute of Electronic Structure and Laser - Foundation for Research and Technology Hellas, (FORTH-IESL) Heraklion, Greece;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Phase Retrieval; Scattering; Optical Projection Tomography; Three Dimensional Imaging; Biomedical Imaging; Image Reconstruction; Turbid Lens; Memory Effect;

    机译：相位检索；散射;光学投影层析成像；三维成像生物医学成像；影像重建;浑浊的镜头;记忆效应;

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